(Q40510958)

21 September 2017

title

A new effector pathway links ATM kinase with the DNA damage response (English)

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21 September 2017

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Constantinos Demonacos

1

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21 September 2017

author name string

Marija Krstic-Demonacos

2

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21 September 2017

Linda Smith

3

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21 September 2017

Danmei Xu

4

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21 September 2017

Darran P O'Connor

5

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21 September 2017

Martin Jansson

6

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21 September 2017

Nicholas B La Thangue

7

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21 September 2017

publication date

19 September 2004

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21 September 2017

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21 September 2017

volume

6

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21 September 2017

issue

10

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21 September 2017

page(s)

968-976

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https://scigraph.springernature.com/pub.10.1038/ncb1170

21 September 2017

exact match

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cites work

The DNA damage response: putting checkpoints in perspective

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Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

ATM, a central controller of cellular responses to DNA damage.

21 January 2018

1 reference

Membrane proteins: Aquaporins--channels without ions.

21 January 2018

1 reference

Cell-cycle checkpoint kinases: checking in on the cell cycle

21 January 2018

1 reference

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

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ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

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Chk2 activates E2F-1 in response to DNA damage

21 January 2018

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

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Regulation of p53 in response to DNA damage

21 January 2018

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p53 mutations in human cancers

21 January 2018

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The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

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Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene

21 January 2018

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Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

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DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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Recruitment of p300/CBP in p53-dependent signal pathways

21 January 2018

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A novel cofactor for p300 that regulates the p53 response

21 January 2018

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A TPR motif cofactor contributes to p300 activity in the p53 response

21 January 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

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Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

21 January 2018

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PI3-kinase inhibition: a target for drug development?

21 January 2018

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53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

21 January 2018

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

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Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

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p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB.

21 January 2018

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1170

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21 September 2017

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