(Q40511072)

21 September 2017

title

HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation (English)

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21 September 2017

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6

Eric A Cohen

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21 September 2017

Manmeet K Mamik

1

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21 September 2017

Elizabeth Hui

2

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21 September 2017

William G Branton

3

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21 September 2017

Brienne A McKenzie

4

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21 September 2017

Jesse Chisholm

5

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21 September 2017

Christopher Power

7

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21 September 2017

publication date

10 October 2016

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Journal of Neuroimmune Pharmacology

21 September 2017

published in

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21 September 2017

volume

12

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21 September 2017

issue

2

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21 September 2017

page(s)

233-248

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https://scigraph.springernature.com/pub.10.1007/s11481-016-9708-3

21 September 2017

exact match

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cites work

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21 January 2018

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21 January 2018

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21 January 2018

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HIV-1 Vpr potently induces programmed cell death in the CNS in vivo.

21 January 2018

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Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

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21 January 2018

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HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration.

21 January 2018

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Gp120-mediated cytotoxicity of human brain microvascular endothelial cells is dependent on p38 mitogen-activated protein kinase activation

21 January 2018

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HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Vpr overcomes macrophage-specific restriction of HIV-1 Env expression and virion production

21 January 2018

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Neurological complications of HIV infection.

21 January 2018

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Involvement of the p53 and p73 transcription factors in neuroAIDS.

21 January 2018

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Chronic systemic IL-1β exacerbates central neuroinflammation independently of the blood-brain barrier integrity

21 January 2018

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Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

21 January 2018

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Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo

21 January 2018

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21 January 2018

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21 January 2018

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IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Role of HIV-1 Vpr in AIDS pathogenesis: relevance and implications of intravirion, intracellular and free Vpr.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Inflammasome activation and IL-1β and IL-18 processing during infection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Brain tumor microvesicles: insights into intercellular communication in the nervous system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Immunodetection of human immunodeficiency virus type 1 (HIV-1) Vpr in brain tissue of HIV-1 encephalitic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-016-9708-3

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

21 January 2018

1 reference

12 December 2020

Vpr in plasma of HIV type 1-positive patients is correlated with the HIV type 1 RNA titers

1 reference

12 December 2020

Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity

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12 December 2020

Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients

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12 December 2020

Mycobacteria Induce IFN- Production in Human Dendritic Cells via Triggering of TLR2

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12 December 2020

Involvement of interleukin-1 in glial responses to lipopolysaccharide: endogenous versus exogenous interleukin-1 actions

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12 December 2020

Effects of extracellular human immunodeficiency virus type 1 vpr protein in primary rat cortical cell cultures.

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12 December 2020

Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.

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12 December 2020

Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells.

1 reference

12 December 2020

Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder

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12 December 2020

Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: inhibition by resveratrol, a polyphenolic phytostilbene

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12 December 2020

Inflammatory cytokine levels are influenced by interactions between THP-1 monocytic, U-373 MG astrocytic, and SH-SY5Y neuronal cell lines of human origin

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12 December 2020

10.1007/S11481-016-9708-3

Identifiers

DOI

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21 September 2017

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