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The inflammasome: in memory of Dr. Jurg Tschopp
scientific article
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instance of
scholarly article
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title
The inflammasome: in memory of Dr. Jurg Tschopp
(English)
0 references
main subject
cell biology
0 references
inflammasome complex
1 reference
based on heuristic
inferred from title
genre
obituary
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author name string
M Dagenais
series ordinal
1
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A Skeldon
series ordinal
2
0 references
M Saleh
series ordinal
3
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language of work or name
English
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publication date
January 2012
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number of pages
8
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based on heuristic
inferred from page(s)
published in
Cell Death & Differentiation
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volume
19
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issue
1
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page(s)
5-12
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cites work
NLRX1/NOD5 deficiency does not affect MAVS signalling
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Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β
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7 April 2017
The inflammasomes
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PubMed Central
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7 April 2017
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
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7 April 2017
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
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PubMed Central
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7 April 2017
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
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PubMed Central
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7 April 2017
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
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PubMed Central
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7 April 2017
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
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PubMed Central
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7 April 2017
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
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PubMed Central
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7 April 2017
The NLR gene family: a standard nomenclature
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PubMed Central
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7 April 2017
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
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PubMed Central
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7 April 2017
SGT1 is essential for Nod1 activation
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PubMed Central
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7 April 2017
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
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7 April 2017
A pilot study of IL-1 inhibition by anakinra in acute gout
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7 April 2017
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
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PubMed Central
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7 April 2017
Structural and functional insights into the B30.2/SPRY domain.
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PubMed Central
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7 April 2017
Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells
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PubMed Central
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7 April 2017
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
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PubMed Central
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7 April 2017
Comparative analysis of apoptosis and inflammation genes of mice and humans
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7 April 2017
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
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7 April 2017
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
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PubMed Central
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7 April 2017
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
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PubMed Central
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7 April 2017
ICEBERG: a novel inhibitor of interleukin-1beta generation
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PubMed Central
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7 April 2017
A role for mitochondria in NLRP3 inflammasome activation
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PubMed Central
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7 April 2017
Gout-associated uric acid crystals activate the NALP3 inflammasome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
The plant immune system
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PubMed Central
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7 April 2017
Principles of bioactive lipid signalling: lessons from sphingolipids
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7 April 2017
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
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7 April 2017
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation
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PubMed Central
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7 April 2017
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
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PubMed Central
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7 April 2017
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
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PubMed Central
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7 April 2017
Death fold domain interaction in apoptosis
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PubMed Central
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7 April 2017
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways
1 reference
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PubMed Central
reference URL
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7 April 2017
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
1 reference
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PubMed Central
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7 April 2017
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
1 reference
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PubMed Central
reference URL
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7 April 2017
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
1 reference
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PubMed Central
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7 April 2017
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
1 reference
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PubMed Central
reference URL
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7 April 2017
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
1 reference
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PubMed Central
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7 April 2017
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
1 reference
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PubMed Central
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7 April 2017
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
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PubMed Central
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7 April 2017
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
1 reference
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PubMed Central
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7 April 2017
Host-microbe interactions: shaping the evolution of the plant immune response
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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7 April 2017
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Mitochondria: Sovereign of inflammation?
1 reference
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PubMed Central
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27 September 2017
Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Regulation of the Apaf-1-caspase-9 apoptosome
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
1 reference
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PubMed Central
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27 September 2017
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity
1 reference
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PubMed Central
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27 September 2017
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Bid: a Bax-like BH3 protein.
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27 September 2017
Use of canakinumab in the cryopyrin-associated periodic syndrome
1 reference
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PubMed Central
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27 September 2017
Immunogenic and tolerogenic cell death
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PubMed Central
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27 September 2017
AMPK: a key regulator of energy balance in the single cell and the whole organism.
1 reference
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27 September 2017
Cell death in the host response to infection
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PubMed Central
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27 September 2017
Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
NLRX1 is a regulator of mitochondrial antiviral immunity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta
1 reference
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PubMed Central
reference URL
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27 September 2017
Pyrin levels in human monocytes and monocyte-derived macrophages regulate IL-1beta processing and release
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
The apoptosome: signalling platform of cell death
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Structure-activity relationships of K(ATP) channel openers
1 reference
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PubMed Central
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27 September 2017
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.
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27 September 2017
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
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PubMed Central
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27 September 2017
CARD15 mutations in Blau syndrome
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PubMed Central
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27 September 2017
The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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27 September 2017
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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30 May 2018
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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30 May 2018
Non-apoptotic role of BID in inflammation and innate immunity.
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PubMed Central
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28 November 2018
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
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28 November 2018
Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling
1 reference
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PubMed Central
reference URL
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28 November 2018
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252823
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28 November 2018
Interaction between the C. elegans cell-death regulators CED-9 and CED-4.
1 reference
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28 November 2018
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
1 reference
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reference URL
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CARD15 gene and the classification of Crohn's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22075986
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22075986
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CDD.2011.159
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3446104
Dimensions Publication ID
1051189984
0 references
OpenCitations bibliographic resource ID
3446104
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3446104
PMC publication ID
3252823
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3446104
PubMed publication ID
22075986
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3446104
ResearchGate publication ID
51791784
0 references
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