(Q40514613)

English

The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation.

scientific article published on 16 September 2004

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15375172%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15375172%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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1 reference

1 reference

prostaglandin E2

1 reference

based on heuristic

inferred from title

Jiiang-Huei Jeng

9

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Europe PubMed Central

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1 January 2020

7

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1 January 2020

8

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Europe PubMed Central

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1 January 2020

author name string

Mei-Chi Chang

1

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1 January 2020

Hui-Lin Wu

2

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1 January 2020

Jang-Jaer Lee

3

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Europe PubMed Central

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1 January 2020

Po-Hsuen Lee

4

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Europe PubMed Central

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1 January 2020

Hsiao-Hwa Chang

5

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1 January 2020

Liang-Jiunn Hahn

6

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1 January 2020

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publication date

16 September 2004

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1 January 2020

number of pages

8

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full work available at URL

http://www.jbc.org/article/S0021925820693504/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1074/jbc.m404465200?email=unpaywall_01@example.com

Journal of Biological Chemistry

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1 January 2020

279

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1 January 2020

49

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1 January 2020

50676-50683

1 reference

Europe PubMed Central

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1 January 2020

online access status

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19 March 2024

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access restriction status

1 reference

based on heuristic

inferred from online access status

Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Prevalence of betel quid chewing habit in Taiwan and related sociodemographic factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Major avoidable risk factors of cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

The incidence of oropharyngeal cancer in Taiwan: an endemic betel quid chewing area.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Betel nut and tobacco chewing; potential risk factors of cancer of oesophagus in Assam, India

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Relationship between site of oesophageal cancer and areca chewing and smoking in Taiwan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Habitual betel quid chewing as a risk factor for cirrhosis: a case-control study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Incidence and cofactors of hepatitis C virus-related hepatocellular carcinoma: a prospective study of 12,008 men in Taiwan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Oesophageal subepithelial fibrosis: an extension of oral submucosal fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Potentiation of genotoxicity by concurrent application of compounds found in betel quid: arecoline, eugenol, quercetin, chlorogenic acid and Mn2+

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Effects of areca nut on growth, differentiation and formation of DNA damage in cultured human buccal epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Cytokines in non-genotoxic hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Review article: inflammation-related promotion of gastrointestinal carcinogenesis--a perigenetic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Coal-induced interleukin-6 gene expression is mediated through ERKs and p38 MAPK pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Reactive oxygen species are crucial for hydroxychavicol toxicity toward KB epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Inhibition of cyclooxygenase-2: an approach to preventing cancer of the upper aerodigestive tract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Prostaglandins and cancer: A review of tumor initiation through tumor metastasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Induction of transcription factor AP-2 by inflammatory cytokines in human keratinocytes.

1 reference

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21 January 2018

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

1 reference

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21 January 2018

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis

1 reference

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21 January 2018

Gene modulation accompanying differentiation of normal versus malignant keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404465200

21 January 2018

Liver cancer in Thailand. I. A case-control study of cholangiocarcinoma

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M404465200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15375172%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15375172%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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