(Q40523453)

English

Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice

scientific article published on 30 July 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

object named as

Ute Hofmann

3

0 references

object named as

Mikko Niemi

4

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author name string

Kari T Kivistö

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Jörg Zukunft

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Sabine Rekersbrink

5

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Swetlana Schneider

6

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Gerd Luippold

7

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Matthias Schwab

8

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Michel Eichelbaum

9

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Martin F Fromm

10

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

1 reference

based on heuristic

publication date

30 July 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

370

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

124-130

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

https://scigraph.springernature.com/pub.10.1007/s00210-004-0948-z

0 references

Mechanistic studies on metabolic interactions between gemfibrozil and statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhabdomyolysis and HMG-CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of the use of statins on the prevalence of dementia and the progression of cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemfibrozil greatly increases plasma concentrations of cerivastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin-fibrate combination therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of cerivastatin in mice, rats, and dogs in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of HMG-CoA reductase inhibitors on skeletal muscle: are all statins the same?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The risk of dementia in relation to statins and other lipid lowering agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical and clinical pharmacology of cerivastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid-Lowering Drugs and Risk of Myopathy: A Population-Based Follow-Up Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of active simvastatin acid are increased by gemfibrozil

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of fibrates on metabolism of statins in human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of rifampin treatment on intestinal expression of human MRP transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerivastatin and reports of fatal rhabdomyolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin-associated memory loss: analysis of 60 case reports and review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms of the human MDR1 drug transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin-associated myopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15322734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-004-0948-Z

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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