(Q40789773)

23 September 2017

HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein (English)

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23 September 2017

Wang E

1

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23 September 2017

Casciano CN

series ordinal

2

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23 September 2017

Clement RP

series ordinal

3

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23 September 2017

Johnson WW

series ordinal

4

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23 September 2017

1 June 2001

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23 September 2017

Pharmaceutical Research

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23 September 2017

18

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23 September 2017

800-806

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23 September 2017

6

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Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membrane

23 September 2017

1 reference

12 December 2020

The mouse multidrug resistance gene family: structural and functional analysis.

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12 December 2020

Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses

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12 December 2020

Erythromycin coadministration increases plasma atorvastatin concentrations

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12 December 2020

Regulation of cholesterol metabolism. I.

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12 December 2020

Extraction of Hoechst 33342 from the cytoplasmic leaflet of the plasma membrane by P-glycoprotein.

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12 December 2020

Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials

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12 December 2020

Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion

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12 December 2020

Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

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12 December 2020

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

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12 December 2020

Massive rhabdomyolysis and simvastatin

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12 December 2020

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

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12 December 2020

Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Human multidrug-resistant (MRP,p190) myeloid leukemia HL-60/ADR cells in vitro: resistance to the mevalonate pathway inhibitor lovastatin.

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12 December 2020

Efficacy and pharmacokinetics of simvastatin in heart transplant recipients

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12 December 2020

P-glycoprotein and multidrug resistance

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12 December 2020

Two transport binding sites of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence

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12 December 2020

Multiple-drug resistance in human cancer

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12 December 2020

Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations

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12 December 2020

P-glycoprotein--a mediator of multidrug resistance in tumour cells

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12 December 2020

Tissue-selective uptake of pravastatin in rats: contribution of a specific carrier-mediated uptake system

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12 December 2020

Cooperativity in the inhibition of P-glycoprotein-mediated daunorubicin transport: evidence for half-of-the-sites reactivity

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12 December 2020

[Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of the hepatic cytochrome P450 enzyme system activity]

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12 December 2020

Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation

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12 December 2020

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats

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12 December 2020

Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter

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12 December 2020

A general pattern for substrate recognition by P-glycoprotein.

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12 December 2020

In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein

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12 December 2020

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

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12 December 2020

Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

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12 December 2020

Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia

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12 December 2020

Stoichiometry of coupling of rhodamine 123 transport to ATP hydrolysis by P-glycoprotein

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12 December 2020

The role of passive transbilayer drug movement in multidrug resistance and its modulation

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12 December 2020

Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein

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12 December 2020

Functional reconstitution of P-glycoprotein reveals an apparent near stoichiometric drug transport to ATP hydrolysis

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12 December 2020

Effect of pravastatin on outcomes after cardiac transplantation.

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12 December 2020

HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: lovastatin specifically targets P-glycoprotein-expressing cells

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12 December 2020

Identifiers

DOI

10.1023/A:1011036428972

1 reference

release_znlp5shebjdf7oleim4y3cuglm

23 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/znlp5shebjdf7oleim4y3cuglm

24 November 2022

mapped directly with Wikidata item

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