(Q40532179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26377465%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26377465%20AND%20SRC:MED&resulttype=core&format=json

blood-cerebrospinal fluid barrier

24 February 2020

main subject

1 reference

7

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24 February 2020

Roosmarijn Vandenbroucke

12

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24 February 2020

Sriram Balusu

2

1 reference

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24 February 2020

Lieve Moons

8

1 reference

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24 February 2020

Selma Kanazir

10

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24 February 2020

author name string

Marjana Brkic

1

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24 February 2020

Elien Van Wonterghem

3

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24 February 2020

Nina Gorlé

4

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24 February 2020

Iryna Benilova

5

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24 February 2020

Anna Kremer

6

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24 February 2020

Claude Libert

11

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24 February 2020

Bart De Strooper

9

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24 February 2020

language of work or name

English

0 references

publication date

1 September 2015

1 reference

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24 February 2020

published in

Journal of Neuroscience

1 reference

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24 February 2020

volume

35

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24 February 2020

issue

37

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24 February 2020

page(s)

12766-12778

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Macromolecules involved in production and metabolism of beta-amyloid at the brain barriers

24 February 2020

cites work

1 reference

12 December 2020

Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.

1 reference

12 December 2020

Is there new hope for therapeutic matrix metalloproteinase inhibition?

1 reference

12 December 2020

MMPs contribute to TNF-alpha-induced alteration of the blood-cerebrospinal fluid barrier in vitro

1 reference

12 December 2020

The effect of intracerebroventricular injection of beta amyloid peptide (1-42) on caspase-3 activity, lipid peroxidation, nitric oxide and NOS expression in young adult and aged rat brain

1 reference

12 December 2020

The pericyte: a forgotten cell type with important implications for Alzheimer's disease?

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12 December 2020

Inflammation and Alzheimer's disease

1 reference

12 December 2020

Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease.

1 reference

12 December 2020

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

12 December 2020

Acute neuroinflammation impairs context discrimination memory and disrupts pattern separation processes in hippocampus

1 reference

12 December 2020

A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced

1 reference

12 December 2020

Monocyte chemoattractant protein-1 in the choroid plexus: a potential link between vascular pro-inflammatory mediators and the CNS during peripheral tissue inflammation

1 reference

12 December 2020

Morphological alterations of the choroid plexus in late-onset Alzheimer's disease.

1 reference

12 December 2020

Blood-brain barrier disruption in multiple sclerosis

1 reference

12 December 2020

Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain.

1 reference

12 December 2020

The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells

1 reference

12 December 2020

Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes

1 reference

12 December 2020

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice.

1 reference

12 December 2020

Choroid plexus: biology and pathology

1 reference

12 December 2020

The blood-brain barrier in health and chronic neurodegenerative disorders

1 reference

12 December 2020

Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy

1 reference

12 December 2020

Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease

1 reference

12 December 2020

Clearance of amyloid-β peptide across the choroid plexus in Alzheimer's disease

1 reference

12 December 2020

Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes

1 reference

12 December 2020

Microglial reactivity to beta-amyloid is modulated by astrocytes and proinflammatory factors

1 reference

12 December 2020

Analysis of matrix metallo-proteases and the plasminogen system in mild cognitive impairment and Alzheimer's disease cerebrospinal fluid

1 reference

12 December 2020

Fiji: an open-source platform for biological-image analysis

1 reference

12 December 2020

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

1 reference

12 December 2020

The choroid plexus response to peripheral inflammatory stimulus.

1 reference

12 December 2020

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

1 reference

12 December 2020

Inflammation of the choroid plexus and ependymal layer of the ventricle following intraventricular hemorrhage

1 reference

12 December 2020

Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein

1 reference

12 December 2020

The choroid plexus in the rise, fall and repair of the brain

1 reference

12 December 2020

Susceptibility of stromelysin 1-deficient mice to collagen-induced arthritis and cartilage destruction

1 reference

12 December 2020

Pericyte loss influences Alzheimer-like neurodegeneration in mice.

1 reference

12 December 2020

Matrix metalloproteinases and their multiple roles in Alzheimer's disease

1 reference

12 December 2020

Alzheimer's beta-amyloid peptide 1-42 induces a phagocytic response in murine microglia

1 reference

12 December 2020

Altered expression of claudin family proteins in Alzheimer's disease and vascular dementia brains

1 reference

12 December 2020

Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease.

1 reference

12 December 2020

Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

1 reference

12 December 2020

Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells

1 reference

12 December 2020

Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences

1 reference

12 December 2020

Increased plasma and tissue MMP levels are associated with BCSFB and BBB disruption evident on post-contrast FLAIR after experimental stroke

1 reference

12 December 2020

Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation

1 reference

12 December 2020

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

1 reference

12 December 2020

Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium

1 reference

12 December 2020

The choroid plexus removes beta-amyloid from brain cerebrospinal fluid

1 reference

12 December 2020

A kinetic study of the cytokine/chemokines levels and disruption of blood-brain barrier in infant rats after pneumococcal meningitis

1 reference

12 December 2020

A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse

1 reference

12 December 2020

Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis

1 reference

12 December 2020

Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change, brain pathology, and functional deficits following traumatic brain injury in the rat.

1 reference

12 December 2020

Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases

1 reference

12 December 2020

Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown

1 reference

12 December 2020

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

1 reference

12 December 2020

Expression of macrophage inflammatory protein 1-alpha is elevated in Alzheimer's vessels and is regulated by oxidative stress

1 reference

12 December 2020

Pathological alteration in the choroid plexus of Alzheimer's disease: implication for new therapy approaches

1 reference

12 December 2020

Inflammatory factors are elevated in brain microvessels in Alzheimer's disease

1 reference

12 December 2020

Matrix metalloproteinase-3 promotes early blood-spinal cord barrier disruption and hemorrhage and impairs long-term neurological recovery after spinal cord injury

1 reference

12 December 2020

Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

1 reference

12 December 2020

Blood-brain-barriers in aging and in Alzheimer's disease

1 reference

12 December 2020

Microglia function in Alzheimer's disease

1 reference

12 December 2020

Clinical implications of leukocyte infiltration at the choroid plexus in (neuro)inflammatory disorders

1 reference

12 December 2020

Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructure

1 reference

12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

1 reference

12 December 2020

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation

1 reference

12 December 2020

Gene expression profile of amyloid beta protein-injected mouse model for Alzheimer disease

1 reference

12 December 2020

Amyloid-β Protein Oligomer at Low Nanomolar Concentrations Activates Microglia and Induces Microglial Neurotoxicity

1 reference

12 December 2020

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

1 reference

12 December 2020

Continuous infusion of beta-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration

1 reference

12 December 2020

Sustained choroid plexus function in human elderly and Alzheimer's disease patients

1 reference

12 December 2020

Activated microglia contribute to the maintenance of chronic pain after spinal cord injury.

1 reference

12 December 2020

Choroid plexus ageing of the brain and Alzheimer s disease

1 reference

12 December 2020

Matrix metalloproteinase-9 leads to claudin-5 degradation via the NF-κB pathway in BALB/c mice with eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis

1 reference

12 December 2020

Cytokines, chemokines, and cytokine receptors in human microglia

1 reference

12 December 2020

Mammalian cell transcriptome in response to meningitis-causing pathogens

1 reference

12 December 2020

Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease

1 reference

12 December 2020

Tight junctions in brain barriers during central nervous system inflammation

1 reference

12 December 2020

The choroid plexus response to a repeated peripheral inflammatory stimulus

1 reference

12 December 2020

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease

1 reference

12 December 2020

A possible role for CSF turnover and choroid plexus in the pathogenesis of late onset Alzheimer's disease

1 reference

12 December 2020

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

1 reference

12 December 2020

Enhancement of blood-brain barrier permeability and reduction of tight junction protein expression are modulated by chemokines/cytokines induced by rabies virus infection.

1 reference

12 December 2020

Concentrations of matrix metalloproteinases and their tissue inhibitors in the cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

12 December 2020

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

1 reference

12 December 2020

10.1523/JNEUROSCI.0006-15.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26377465%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

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24 February 2020

PubMed publication ID

26377465

1 reference