(Q40532718)

English

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.

scientific article published on July 2004

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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Anders Björklund

3

object named as

Anders Björklund

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Biljana Georgievska

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Deniz Kirik

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Anders Björklund

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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publication date

1 July 2004

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

29

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

6437-6445

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intra-striatal GDNF on motor coordination and striatal electrophysiology in aged F344 rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine autoreceptors modulate the phosphorylation of tyrosine hydroxylase in rat striatal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional activity of substantia nigra grafts reinnervating the striatum: neurotransmitter metabolism and [14C]2-deoxy-D-glucose autoradiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor: the lateral cerebral ventricle as a site of administration for stimulation of the substantia nigra dopamine system in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intricate regulation of tyrosine hydroxylase activity and gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopaminergic neurons protected from degeneration by GDNF gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor: distribution and pharmacology in the rat following a bolus intraventricular injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor induces the dopaminergic and cholinergic phenotype and increases locomotor activity in aged Fischer 344 rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and neurochemical effects of intranigral administration of glial cell line-derived neurotrophic factor on aged Fischer 344 rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor prevents death, but not reductions in tyrosine hydroxylase, of injured nigrostriatal neurons in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective and neurorestorative properties of GDNF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15269253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1122-04.2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15269253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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