(Q40533674)

21 September 2017

title

Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways (English)

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21 September 2017

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4

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21 September 2017

Hirohito Yamaguchi

1

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21 September 2017

Jiandong Chen

series ordinal

2

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21 September 2017

Kapil Bhalla

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

19 July 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

38

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21 September 2017

page(s)

39431-39437

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21 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M401530200

Microtubule-targeted anticancer agents and apoptosis

21 January 2018

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The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401530200

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401530200

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

21 January 2018

1 reference

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Breaking the mitochondrial barrier

21 January 2018

1 reference

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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21 January 2018

Surfing the p53 network

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Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

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P53 and radiation responses

21 January 2018

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

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BID regulation by p53 contributes to chemosensitivity

21 January 2018

1 reference

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p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

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The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

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Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

21 January 2018

1 reference

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Inactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicity

21 January 2018

1 reference

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Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics

21 January 2018

1 reference

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Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells

21 January 2018

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Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells

21 January 2018

1 reference

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

21 January 2018

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Role of BAX in the apoptotic response to anticancer agents

21 January 2018

1 reference

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Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

1 reference

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401530200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401530200

1 reference

21 September 2017

1 reference