(Q40539163)

21 September 2017

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title

P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer (English)

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21 September 2017

Nedelcheva V

1

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21 September 2017

Gut I

series ordinal

2

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21 September 2017

language of work or name

English

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publication date

1 December 1994

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21 September 2017

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21 September 2017

volume

24

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21 September 2017

issue

12

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21 September 2017

page(s)

1151-1175

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Induction of cytochromes P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Induction of microsomal cytochrome P-450 enzymes: the first Bernard B. Brodie lecture at Pennsylvania State University

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

17 beta-estradiol 2- and 4-hydroxylation catalyzed by rat hepatic cytochrome P-450: roles of individual forms, inductive effects, developmental patterns, and alterations by gonadectomy and hormone replacement.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Molecular genetics of the P-450 superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Enzyme induction in the cytochrome P-450 system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Preparation and characterization of monoclonal antibodies to pregnenolone 16-alpha-carbonitrile inducible rat liver cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Purification and characterization of hepatic microsomal cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Steroid metabolism by constitutive cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Selective mutagenic activation by cytochrome P3-450 of carcinogenic arylamines found in foods.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cytochromes P-450 in rats: structures, functions, properties and relevant human forms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylainine to products genotoxic in an acetyltransferase–overexpressing Salmonella typhimurium strain (NM2009)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Specificity of four forms of cytochrome P-450 in the metabolic activation of several aromatic amines and benzo[a]pyrene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259409038673

10.3109/00498259409038673

21 January 2018

Identifiers

DOI

1 reference

21 September 2017

1 reference