(Q40559486)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572165%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis (English)

1 reference

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21 March 2020

12

1 reference

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21 March 2020

Mary Speir

1

1 reference

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21 March 2020

Kate E. Lawlor

2

1 reference

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21 March 2020

Seong H Chow

5

1 reference

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21 March 2020

Keith E Schulze

7

1 reference

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21 March 2020

Elizabeth L. Hartland

11

1 reference

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21 March 2020

David C Huang

15

1 reference

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21 March 2020

author name string

Stefan P Glaser

3

1 reference

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21 March 2020

Gilu Abraham

4

1 reference

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21 March 2020

Adam Vogrin

6

1 reference

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21 March 2020

Ralf Schuelein

8

1 reference

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21 March 2020

Lorraine A O'Reilly

9

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21 March 2020

Guillaume Lessene

14

1 reference

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21 March 2020

James E Vince

16

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21 March 2020

Thomas Naderer

17

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21 March 2020

Kylie Mason

10

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21 March 2020

Andreas Strasser

13

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21 March 2020

publication date

24 February 2016

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21 March 2020

1 reference

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21 March 2020

volume

1

1 reference

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21 March 2020

page(s)

15034

1 reference

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https://scigraph.springernature.com/pub.10.1038/nmicrobiol.2015.34

21 March 2020

exact match

0 references

cites work

Molecular pathogenesis of infections caused by Legionella pneumophila

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Aggravating genetic interactions allow a solution to redundancy in a bacterial pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Public health and economic costs of investigating a suspected outbreak of Legionnaires' disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

BCL-2 family antagonists for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Rapid turnover of mcl-1 couples translation to cell survival and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Host translation at the nexus of infection and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Control of Legionella in hospitals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

Experimental Legionella longbeachae infection in intratracheally inoculated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

21 January 2018

Legionnaires' disease

1 reference

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2015.34

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMICROBIOL.2015.34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572165%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference