(Q38053751)

27 August 2017

1 reference

22 August 2022

Host translation at the nexus of infection and immunity (English)

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27 August 2017

2

Nahum Sonenberg

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27 August 2017

Ian Mohr

1

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27 August 2017

1 October 2012

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PubMed ID

23084916

27 August 2017

18 October 2012

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22 August 2022

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27 August 2017

22 August 2022

12

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27 August 2017

4

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27 August 2017

470-483

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Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

27 August 2017

1 reference

12 December 2020

Small self-RNA generated by RNase L amplifies antiviral innate immunity

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12 December 2020

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1

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12 December 2020

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut.

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12 December 2020

Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways

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12 December 2020

Apicomplexan parasites and subversion of the host cell microRNA pathway

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12 December 2020

Interferon-inducible antiviral effectors

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12 December 2020

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

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12 December 2020

GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor

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12 December 2020

Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family

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12 December 2020

Translational control of the innate immune response through IRF-7

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12 December 2020

mTOR signaling in growth control and disease

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12 December 2020

Assembly of an active translation initiation factor complex by a viral protein

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12 December 2020

Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state

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12 December 2020

The viral and cellular microRNA targetome in lymphoblastoid cell lines

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12 December 2020

Activation of GCN2 in UV-irradiated cells inhibits translation

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12 December 2020

mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.

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12 December 2020

Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression

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12 December 2020

Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor.

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12 December 2020

Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans

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12 December 2020

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

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12 December 2020

Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F

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12 December 2020

Viruses, microRNAs, and host interactions

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12 December 2020

Vaccinia virus D10 protein has mRNA decapping activity, providing a mechanism for control of host and viral gene expression

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12 December 2020

Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection

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12 December 2020

Diverse virus-host interactions influence RNA-based regulation during γ-herpesvirus infection

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12 December 2020

Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection

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12 December 2020

Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology

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12 December 2020

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

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12 December 2020

Nature and duration of growth factor signaling through receptor tyrosine kinases regulates HSV-1 latency in neurons.

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12 December 2020

Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA

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12 December 2020

Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors.

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12 December 2020

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.

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12 December 2020

Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo

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12 December 2020

Mechanistic role of structurally dynamic regions in Dicistroviridae IGR IRESs

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12 December 2020

Drosophila melanogaster Thor and response to Candida albicans infection.

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12 December 2020

A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function

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12 December 2020

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

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12 December 2020

Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

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12 December 2020

Non-conventional sources of peptides presented by MHC class I.

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12 December 2020

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

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12 December 2020

Modification of eukaryotic initiation factor 4F during infection by influenza virus.

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12 December 2020

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

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12 December 2020

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection

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12 December 2020

A common strategy for host RNA degradation by divergent viruses

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12 December 2020

Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency.

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12 December 2020

bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans

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12 December 2020

Human cytomegalovirus infection activates and regulates the unfolded protein response

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12 December 2020

The elongation, termination, and recycling phases of translation in eukaryotes

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12 December 2020

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

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12 December 2020

Activation of the unfolded protein response by Listeria monocytogenes

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12 December 2020

Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.

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12 December 2020

Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis

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12 December 2020

Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases.

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12 December 2020

Viral subversion of the host protein synthesis machinery

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12 December 2020

Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses

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12 December 2020

Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.

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12 December 2020

Increased susceptibility to DNA virus infection in mice with a GCN2 mutation

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12 December 2020

Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion

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12 December 2020

Mutational analysis of the EMCV 2A protein identifies a nuclear localization signal and an eIF4E binding site

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12 December 2020

Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.

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12 December 2020

miR-146a mediates protective innate immune tolerance in the neonate intestine

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12 December 2020

Endoplasmic reticulum stress pathway-mediated apoptosis in macrophages contributes to the survival of Mycobacterium tuberculosis

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12 December 2020

Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines

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12 December 2020

Protein kinase R reveals an evolutionary model for defeating viral mimicry

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12 December 2020

Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase

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12 December 2020

Regulation of protein translation through mRNA structure influences MHC class I loading and T cell recognition.

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12 December 2020

Molecular mechanism of scanning and start codon selection in eukaryotes

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12 December 2020

Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cells

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12 December 2020

Characterization of a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression

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12 December 2020

Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR.

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12 December 2020

mRNA helicases: the tacticians of translational control

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12 December 2020

Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products.

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12 December 2020

Leucine-tRNA initiates at CUG start codons for protein synthesis and presentation by MHC class I

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12 December 2020

Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism

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12 December 2020

Stable formation of compositionally unique stress granules in virus-infected cells.

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12 December 2020

A frameshift mutation at the NH2 terminus of the nucleoprotein gene does not affect generation of cytotoxic T lymphocyte epitopes

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12 December 2020

The TSC-mTOR signaling pathway regulates the innate inflammatory response

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12 December 2020

Poly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells

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12 December 2020

Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells

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12 December 2020

Self-inhibition of synthesis and antigen presentation by Epstein-Barr virus-encoded EBNA1.

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12 December 2020

Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cells

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12 December 2020

The mechanism of eukaryotic translation initiation: new insights and challenges

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12 December 2020

microRNA regulation of inflammatory responses

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12 December 2020

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

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12 December 2020

Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans

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12 December 2020

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

1 reference

12 December 2020

An overlapping protein-coding region in influenza A virus segment 3 modulates the host response

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12 December 2020

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses

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12 December 2020

Suppression of the microRNA pathway by bacterial effector proteins

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12 December 2020

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

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12 December 2020

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B.

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12 December 2020

Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor

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12 December 2020

Differential protein expression of murine macrophages upon interaction with Candida albicans

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12 December 2020

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

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12 December 2020

Initiation of protein synthesis from the A site of the ribosome

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12 December 2020

P-bodies and stress granules: possible roles in the control of translation and mRNA degradation

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12 December 2020

Recessive resistance to plant viruses.

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12 December 2020

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

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12 December 2020

MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy

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12 December 2020

Synthesis of Proteins and Glycoproteins in Cells Infected with Human Cytomegalovirus

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12 December 2020

Viral latency and its regulation: lessons from the gamma-herpesviruses

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12 December 2020

EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency

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12 December 2020

Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses

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12 December 2020

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

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12 December 2020

Dcp2 decapping protein modulates mRNA stability of the critical interferon regulatory factor (IRF) IRF-7.

1 reference

12 December 2020

Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.

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12 December 2020

The African swine fever virus g5R protein possesses mRNA decapping activity

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12 December 2020

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk

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12 December 2020

The plant immune system

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12 December 2020

Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.

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12 December 2020

DRiPs solidify: progress in understanding endogenous MHC class I antigen processing

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12 December 2020

Induction of ER stress in macrophages of tuberculosis granulomas

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12 December 2020

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

1 reference

12 December 2020

Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E.

1 reference

12 December 2020

Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor.

1 reference

12 December 2020

The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation

1 reference

12 December 2020

Signal integration in the endoplasmic reticulum unfolded protein response

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12 December 2020

The role of type I interferons in non-viral infections

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12 December 2020

Host immune system gene targeting by a viral miRNA

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12 December 2020

An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination

1 reference

12 December 2020

C. elegans detects pathogen-induced translational inhibition to activate immune signaling

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12 December 2020

Distinct patterns of IFN sensitivity observed in cells infected with vaccinia K3L- and E3L- mutant viruses

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12 December 2020

Regulation of stress granules in virus systems

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12 December 2020

Intracellular pathogenic bacteria and fungi--a case of convergent evolution?

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12 December 2020

Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells.

1 reference

12 December 2020

A cultured affair: HSV latency and reactivation in neurons

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12 December 2020

Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling

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12 December 2020

10.1016/J.CHOM.2012.09.006

Identifiers

DOI

1 reference

27 August 2017

0 references

1 reference

PubMed ID

23084916