(Q40569589)

English

Modulation of insulin receptor signalling: significance of altered receptor isoform patterns and mechanism of hyperglycaemia-induced receptor modulation

scientific article published on September 1994

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

Modulation of insulin receptor signalling: significance of altered receptor isoform patterns and mechanism of hyperglycaemia-induced receptor modulation (English)

1 reference

Europe PubMed Central

21 September 2017

1 reference

based on heuristic

inferred from title

Hans-Ulrich Häring

1

object named as

H U Häring

1 reference

Europe PubMed Central

21 September 2017

author name string

M Kellerer

2

1 reference

Europe PubMed Central

21 September 2017

L Mosthaf

3

1 reference

Europe PubMed Central

21 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 September 1994

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

37 Suppl 2

1 reference

Europe PubMed Central

21 September 2017

S149-54

1 reference

Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1007/bf00400838

0 references

Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: candidates for a signal transmitter defect causing insulin resistance of the skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamines and tumour promoting phorbolesters inhibit insulin receptor kinase and induce insulin resistance in isolated human adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-sensitive tyrosine kinase: relationship with in vivo insulin action in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence That Two Naturally Occurring Human Insulin Receptor α-Subunit Variants Are Immunologically Distinct

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor isotype expression correlates with risk of non-insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The two isotypes of the human insulin receptor (HIR-A and HIR-B) follow different internalization kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. The RNA variant without Exon 11 predominates in both groups.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol-3-kinase by insulin is mediated by both A and B human insulin receptor types

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally distinct insulin receptors generated by tissue-specific alternative splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformation polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of NIDDM. A balanced overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing of human insulin receptor messenger RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inositol phospho-oligosaccharides from rat fibroblasts and adipocytes stimulate 3-O-methylglucose transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular distribution of GLUT 4 in the skeletal muscle of lean type 2 (non-insulin-dependent) diabetic patients in the basal state

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of phospholipase C activity by insulin is mediated by both isotypes of the human insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NIDDM Associated With Mutation in Tyrosine Kinase Domain of Insulin Receptor Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct alpha-subunit structures of human insulin receptor A and B variants determine differences in tyrosine kinase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/7821730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00400838

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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