(Q40580491)

English

Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.

scientific article published on 9 March 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15010462%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15010462%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

phosphorylation

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based on heuristic

inferred from title

Gustavo Mostoslavsky

2

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Europe PubMed Central

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25 December 2019

Kenneth C. Anderson

10

object named as

Kenneth C Anderson

1 reference

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25 December 2019

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Klaus Podar

1

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25 December 2019

Martin Sattler

3

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25 December 2019

Yu-Tzu Tai

4

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25 December 2019

Toshiaki Hayashi

5

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25 December 2019

Laurence P Catley

6

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25 December 2019

Teru Hideshima

7

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25 December 2019

Richard C Mulligan

8

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25 December 2019

Dharminder Chauhan

9

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25 December 2019

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publication date

9 March 2004

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25 December 2019

Journal of Biological Chemistry

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25 December 2019

279

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25 December 2019

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25 December 2019

21658-21665

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25 December 2019

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

The gift of Gab.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Critical role for Gab2 in transformation by BCR/ABL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Gab3, a new DOS/Gab family member, facilitates macrophage differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Protein tyrosine phosphatases in signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Protein tyrosine phosphatases in signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Genetic analysis of protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

The specificities of protein kinase inhibitors: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Stimulation of endogenous GH and interleukin-6 receptors selectively activates different Jaks and Stats, with a Stat5 specific synergistic effect of dexamethasone.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Signaling mechanisms through gp130: a model of the cytokine system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Coupling kinase activation to substrate recognition in SRC-family tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Essential role of Gab1 for signaling by the c-Met receptor in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Essential role for Gab2 in the allergic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Isolation and characterization of human multiple myeloma cell enriched populations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Ku86 variant expression and function in multiple myeloma cells is associated with increased sensitivity to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Epidermal Growth Factor-induced DNA Synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305783200

21 January 2018

Identifiers

10.1074/JBC.M305783200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15010462%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15010462%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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