(Q40586884)

21 September 2017

title

Distinct mechanisms lead to HPRT gene mutations in leukemic cells (English)

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21 September 2017

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4

Peter D Aplan

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21 September 2017

Ying-Wei Lin

1

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21 September 2017

Jonathan J Perkins

series ordinal

2

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21 September 2017

Zhenhua Zhang

series ordinal

3

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21 September 2017

publication date

1 April 2004

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Genes, Chromosomes and Cancer

21 September 2017

published in

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21 September 2017

volume

39

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21 September 2017

issue

4

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21 September 2017

page(s)

311-323

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Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.

21 September 2017

cites work

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A fast and simple method to determine the clonal relationship among human T-cell lymphocytes.

21 January 2018

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Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age.

21 January 2018

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Fine structure of the human hypoxanthine phosphoribosyltransferase gene

21 January 2018

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X-ray-induced mutation to 6-thioguanine resistance in cultured human diploid fibroblasts

21 January 2018

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Normal mutation frequencies of somatic cells in patients receiving growth hormone therapy

21 January 2018

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HPRT mutations in humans: biomarkers for mechanistic studies

21 January 2018

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7 January 2021

T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

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Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.

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Forty years of decoding the silence in X-chromosome inactivation

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Rapid, nonradioactive detection of clonal T-cell receptor gene rearrangements in lymphoid neoplasms

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The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2.

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The spontaneous azaguanine-resistant mutants of diploid human fibroblasts.

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Maintenance of an open reading frame as an additional level of scrutiny during splice site selection

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DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

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7 January 2021

Emergence of genetic instability in children treated for leukemia.

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7 January 2021

Bloom's syndrome. XX. The first 100 cancers

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Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families

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7 January 2021

Mismatch repair deficiency in hematological malignancies with microsatellite instability

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7 January 2021

Rules for making human tumor cells

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7 January 2021

Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin

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7 January 2021

Establishment of an Epstein-Barr Virus-Determined Nuclear Antigen-Negative Human B-Cell Line From Acute Lymphoblastic Leukemia: Brief Communication2

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7 January 2021

Implication of protein kinase C in the regulation of DNA mismatch repair protein expression and function

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7 January 2021

Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase

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7 January 2021

Molecular cytogenetic analysis of the monoblastic cell line U937. karyotype clarification by G-banding, whole chromosome painting, microdissection and reverse painting, and comparative genomic hybridization

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7 January 2021

Genetic instabilities in human cancers

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7 January 2021

Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents.

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7 January 2021

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

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7 January 2021

Isolation and characterisation of a CDw50 negative Jurkat T-cell line variant (PPL.1).

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7 January 2021

Identity of original and late passage Dami megakaryocytes with HEL erythroleukemia cells shown by combined cytogenetics and DNA fingerprinting

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7 January 2021

Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype

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7 January 2021

The power of point mutations

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7 January 2021

The karyotype of the glucocorticoid-sensitive, lymphoblastic human T-cell line CCRF-CEM shows a unique deleted and inverted chromosome 9.

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7 January 2021

A catalogue of splice junction sequences

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7 January 2021

Complete karyotype characterization of the K562 cell line by combined application of G-banding, multiplex-fluorescence in situ hybridization, fluorescence in situ hybridization, and comparative genomic hybridization

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7 January 2021

Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans.

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7 January 2021

Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene

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7 January 2021

Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation

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7 January 2021

How many mutations are required for tumorigenesis? Implications from human cancer data

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7 January 2021

Population analysis of karyotypic heterogeneity of the Raji Burkitt lymphoma cell line. Analysis of 100 karyotypes

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7 January 2021

Short-term storage of blood samples and DNA isolation in serum separator tubes for application in epidemiological studies and clinical research

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7 January 2021

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

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7 January 2021

ML-1 cell line lacks a germline MLL locus

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7 January 2021

Characterization of MLH1 and MSH2 DNA mismatch repair proteins in cell lines of the NCI anticancer drug screen

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7 January 2021

More detailed characterization of some of the HL60 karyotypic features by fluorescence in situ hybridization.

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7 January 2021

Small changes in expression affect predisposition to tumorigenesis

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7 January 2021

Identifiers

DOI

10.1002/GCC.20005

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21 September 2017

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