(Q40590057)

21 September 2017

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span (English)

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21 September 2017

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1 reference

Gabriele Saretzki

2

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Thomas von Zglinicki

object named as

Thomas von Zglinicki

8

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Carmen M Martin-Ruiz

1

object named as

Carmen Martin-Ruiz

1 reference

21 September 2017

5

Jessie Jeyapalan

1 reference

21 September 2017

Joanne Petrie

3

1 reference

21 September 2017

Juliane Ladhoff

4

1 reference

21 September 2017

Wenyi Wei

6

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21 September 2017

John Sedivy

7

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21 September 2017

language of work or name

English

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publication date

12 February 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

17826-17833

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21 September 2017

17

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Switching and signaling at the telomere

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Historical claims and current interpretations of replicative aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Telomere states and cell fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Oxidative stress shortens telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

BRENDA, enzyme data and metabolic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Human skin fibroblasts in vitro differentiate along a terminal cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Ceroid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Extensive allelic variation and ultrashort telomeres in senescent human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Different telomere damage signaling pathways in human and mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Reversal of human cellular senescence: roles of the p53 and p16 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Evidence that exposure of the telomere 3' overhang sequence induces senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Telomerase maintains telomere structure in normal human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Developmental differences in the immortalization of lung fibroblasts by telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

Accelerated telomere shortening in fibroblasts after extended periods of confluency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

The old worm turns more slowly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311980200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311980200

1 reference

21 September 2017

1 reference