(Q40596146)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

review article

1 reference

title

Cellular resistance to cancer chemotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

3

1 reference

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27 October 2019

author name string

T Skovsgaard

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

D Nielsen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

K Wassermann

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

publication date

1 January 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

International Review of Cytology

27 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

volume

156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

page(s)

77-157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro

27 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Intensely potent morpholinyl anthracyclines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The cell biology of multiple drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA crosslinking by 3'-(3-cyano-4-morpholinyl)-3'-deaminoadriamycin in HT-29 human colon carcinoma cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Over-expression of MDR1 gene with no DNA amplification in a multiple-drug-resistant human ovarian carcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Folate antagonists: toward improving the therapeutic index and development of new analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of human glutathione S-transferases in Saccharomyces cerevisiae confers resistance to the anticancer drugs adriamycin and chlorambucil

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Evidence for Two Molecular Species of Dihydrofolate Reductase in Amethopterin Resistant and Sensitive Cells of the Mouse Leukemia L4946

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Human repair gene restores normal pattern of preferential DNA repair in repair defective CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanism of multidrug resistance in human tumour cell lines and complete reversion of cellular resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Genetic mechanisms of drug resistance. A review

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Loss of viability and induction of DNA damage in human leukemic myeloblasts and lymphocytes by m-AMSA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Immunohistochemical detection of P-glycoprotein in human tumor cells with a low degree of drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Amino acid substitutions in the human glutathione S-transferases confer different specificities in the prostaglandin endoperoxide conversion pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Isolation of a polymorphic genomic clone from chromosome 7. Physical and genetic linkage studies to markers around the cystic fibrosis locus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Characterization of an unusual mutant of human melanoma cells resistant to anticancer drugs that inhibit topoisomerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Modulation of membrane drug permeability in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Resistance to methotrexate due to gene amplification in a patient with acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Drug resistance in oncology: from concepts to applications.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Identification of inducible damage-recognition proteins that are overexpressed in HeLa cells resistant to cis-diamminedichloroplatinum (II).

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Damage-recognition proteins as a potential indicator of DNA-damage-mediated sensitivity or resistance of human cells to ultraviolet radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Reduced DNA topoisomerase II activity and drug-stimulated DNA cleavage in 9-hydroxyellipticine resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cytofluorescence localization of adriamycin in resistant colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

N-(5,5-diacetoxypent-1-yl)doxorubicin: a new intensely potent doxorubicin analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Topoisomerase-specific drug sensitivity in relation to cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

COMPARATIVE STUDIES OF LEUKEMIC CELLS SENSITIVE AND RESISTANT TO CYTOSINE ARABINOSIDE.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Correlation between anthracycline structure and human DNA ligase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Retention of activity by selected anthracyclines in a multidrug resistant human large cell lung carcinoma line without P-glycoprotein hyperexpression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Regulation of topoisomerase II by murine mastocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The inhibition of repair in UV irradiated human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Doxorubicin-loaded nanospheres bypass tumor cell multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Determinants of cisplatin sensitivity in non-malignant non-drug-selected human T cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A protein factor that enhances amsacrine-mediated formation of topoisomerase II-DNA complexes in murine mastocytoma cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Evidence that a protein kinase enhances amsacrine mediated formation of topoisomerase II-DNA complexes in murine mastocytoma cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Studies on 1-beta-D-arabinofuranosyl-cytosine (Ara-C) resistant mutants of Chinese hamster fibroblasts. II. High resistance to Ara-C as a genetic marker for cellular hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Methotrexate-resistant human promyelocytic leukemia (HL-60) cells express a dihydrofolate reductase with altered properties associated with increased enzyme activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Toremifene: pharmacologic and pharmacokinetic basis of reversing multidrug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A model for computer simulation of P-glycoprotein and transmembrane delta pH-mediated anthracycline transport in multidrug-resistant tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Antifolate transport in L1210 leukemia cells. Kinetic evidence for the non-identity of carriers for influx and efflux

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Studies on drug resistance—II. Kinase patterns in P815 neoplasms sensitive and resistant to 1-β-d-arabinofuranosylcytosine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerases from rat liver: physiological variations

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Novobiocin enhances alkylating agent cytotoxicity and DNA interstrand crosslinks in a murine model

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Etoposide-induced DNA cleavage in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The biochemistry of P-glycoprotein-mediated multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cell cycle stage dependent variations in drug-induced topoisomerase II mediated DNA cleavage and cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Detective transport of amethopterin (methotrexate) as a mechanism of resistance to the antimetabolite in L5178Y leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Doxorubicin inhibits human DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of a multidrug-resistance gene in human tumors and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Effect of 1-beta-D-arabinofuranosyl cytosine and hydroxyurea on the repair of X-ray-induced DNA single-strand breaks in human leukemic blasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Classification of chemical agents as to their ability to induce long-or short-patch DNA repair in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Inhibition of DNA repair and the enhancement of cytotoxicity of alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

In vitro circumvention of anthracycline--resistance in Ehrlich ascites tumour by anthracycline analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular do

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Ultrastructural alterations in plasma membranes from drug-resistant P388 murine leukemia cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase pi gene expression in primary and relapsed state adult and childhood leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The cellular pharmacology of methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of a multidrug resistance gene in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Abnormal chloride conductance in multidrug resistant HL60/AR cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

On the nature of permeability of sarcoma-180 cells to amethopterin in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Membrane potential differences between adriamycin-sensitive and -resistant cells as measured by flow cytometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

5-Bromodeoxyuridine-dependent increase in sister chromatid exchange formation in Bloom's syndrome is associated with reduction in topoisomerase II activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Inhibitory effects of probenecid on the individual transport routes which mediate the influx and efflux of methotrexate in L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Comparative study of 6-mercaptopurine metabolism in human leukemic leukocytes and L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Identification of a multidrug resistance associated antigen (P-glycoprotein) in normal human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

P-glycoprotein overexpression cannot explain the complete doxorubicin-resistance phenotype in rat glioblastoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Glycosylation of P-glycoprotein in a multidrug-resistant KB cell line, and in the human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Structural and functional analyses of the promoter of the murine multidrug resistance gene mdr3/mdr1a reveal a negative element containing the AP-1 binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Acquired methotrexate resistance in lymphoblasts resulting from altered kinetic properties of dihydrofoltate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

In vitro repair of single-strand breaks in -irradiated DNA by polynucleotide ligase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Doxorubicin sensitivity pattern in a panel of small-cell lung-cancer cell lines: correlation to etoposide and vincristine sensitivity and inverse correlation to carmustine sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

3'-(3-Cyano-4-morpholinyl)-3'-deaminoadriamycin: a new anthracycline with intense potency

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Overexpressed human metallothionein IIA gene protects Chinese hamster ovary cells from killing by alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

MDR1 RNA levels in human renal cell carcinomas: correlation with grade and prediction of reversal of doxorubicin resistance by quinidine in tumor explants

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Isolation of amplified DNA sequences from IMR-32 human neuroblastoma cells: facilitation by fluorescence-activated flow sorting of metaphase chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanisms involved in the development of adriamycin resistance in human leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Increased cytosolic pH in multidrug-resistant human lung tumor cells: effect of verapamil.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Overexpression of metallothionein confers resistance to anticancer drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Uptake as a Determinant of Methotrexate Response in Mouse Leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The direct activation of human multidrug resistance gene (MDR1) by anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Evidence for daunomycin efflux from multidrug-resistant 2780AD human ovarian carcinoma cells against a concentration gradient

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Verapamil and cyclosporin A potentiate the effects of chemotherapeutic drugs in the human medullary thyroid carcinoma TT cell line not expressing the 170 kDa P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The metabolism of α-2′ -deoxythioguanosine in murine tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Sensitization of drug resistant human ovarian cancer cells to cyanomorpholino doxorubicin (MRA-CN) by modulation of glutathione metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Clinical Science Review: Update on Trimetrexate, a Folate Antagonist with Antineoplastic and Antiprotozoal Properties

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase poisons as antitumor drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of phenotypic traits following modulation of colchicine resistance in J774.2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Reduced occurrence of mdr-1 amplification in stage-IV breast-cancer patients treated with tamoxifen compared with other endocrine treatments

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Appearance and detection of multiple copies of the mdr-1 gene in clinical samples of mammary carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Alkylation damage, DNA repair and mutagenesis in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Dihydrofolate reductase activity in adriamycin and methotrexate sensitive and resistant P388 leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Localization of the multidrug resistance-associated 170 kDa P-glycoprotein gene to mouse chromosome 5 and to homogeneously staining regions in multidrug-resistant mouse cells by in situ hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Repair analysis of mitomycin C-induced DNA crosslinking in ribosomal RNA genes in lymphoblastoid cells from Fanconi's anemia patients

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Reversal of melphalan resistance in vivo and in vitro by modulation of glutathione metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Phenotypic Expression in Escherichia coli and Nucleotide Sequence of Two Chinese Hamster Lung Cell cDNAs Encoding Different Dihydrofolate Reductases

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Analysis of dihydrofolate reductase gene amplification in a methotrexate-resistant human tumor cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Deoxyribonucleotide Pools in Mouse-Fibroblast Cell Lines with Altered Ribonucleotide Reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

mdr-1 gene amplification in acute lymphoblastic leukaemia prior to antileukaemic treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Epidermal growth factor-induced topoisomerase(s). Intracellular translocation and relation to DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Effect of staurosporine derivatives on protein kinase activity and vinblastine accumulation in mouse leukaemia P388/ADR cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

P-glycoprotein as multidrug transporter: a critical review of current multidrug resistant cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Changes of molecular properties associated with the development of resistance against methotrexate in human lymphoblastoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Multidrug resistance (mdr) genes in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Structure and genomic organization of the mouse dihydrofolate reductase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Doxorubicin selected multidrug-resistant small cell lung cancer cell lines characterised by elevated cytoplasmic Ca2+ and resistance modulation by verapamil in absence of P-glycoprotein overexpression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Catalytic function of DNA topoisomerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cytosine arabinoside: molecular, pharmacokinetic and cytokinetic considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Clinical relevance of biochemical modulation of 5-fluorouracil

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Fluorouracil: biochemistry and pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Host-cell reactivation of cis-diamminedichloroplatinum(II)-treated SV40 DNA in normal human, Fanconi anaemia and xeroderma pigmentosum fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase I and II in cancer chemotherapy: update and perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Verapamil reversal of clinical doxorubicin resistance in human cancer. A Wilshire Oncology Medical Group pilot phase I-II study

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Doxorubicin resistance in P388 leukemia--evidence for reduced drug influx.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Non-P-glycoprotein-mediated multidrug resistance with reduced EGF receptor expression in a human large cell lung cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Immunohistochemical analysis of P-glycoprotein expression correlated with chemotherapy resistance in locally advanced breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

From amplification to function: the case of the MDR1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Protein-associated DNA breaks in cells treated with adriamycin or ellipticine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerases as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A protein kinase activity tightly associated with Drosophila type II DNA topoisomerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Expression of MDR1 and glutatione S transferase-π genes and chemosensitivities in human gastrointestinal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Taxol-dependent mutants of Chinese hamster ovary cells with alterations in alpha- and beta-tubulin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Methotrexate polyglutamate synthesis by cultured human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Gene amplification in cultured animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanism of resistance of non-cycling mammalian cells to 4'-[9-acridinylamino]methanesulphon-m-anisidide: role of DNA topoisomerase II in log- and plateau-phase CHO cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Increased activity of alkaline phosphatase in leukemic cells from patients resistant to thiopurines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Potentiation of doxorubicin cytotoxicity by the calcium antagonist bepridil in anthracycline-resistant and -sensitive cell lines. A comparison with verapamil.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Quantitative determination of factors contributing to doxorubicin resistance in multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Increase in nonspecific adsorptive endocytosis in anthracycline- and vinca alkaloid-resistant Ehrlich ascites tumor cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The carboxylic ionophore monensin inhibits active drug efflux and modulates in vitro resistance in daunorubicin resistant Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Daunorubicin and vincristine binding to plasma membrane vesicles from daunorubicin-resistant and wild type Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Carbon-7 substituted actinomycin D analogues as improved antitumor agents: synthesis and DNA-binding and biological properties

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA repair in cells sensitive and resistant to cis-diamminedichloroplatinum(II): host cell reactivation of damaged plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Production of a site specifically cleavable P-glycoprotein-.BETA.-galactosidase fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Comparison of anthracycline concentrations in S180 cell lines of varying sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Dissociation of antitumor potency from anthracycline cardiotoxicity in a doxorubicin analog.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Etoposide-induced DNA damage in human tumor cells: requirement for cellular activating factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Markedly altered membrane transport and intracellular binding of vincristine in multidrug-resistant Chinese hamster cells selected for resistance to vinca alkaloids.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Chemosensitizers counteracting acquired resistance to anthracyclines and vinca alkaloidsin vivo. A new treatment principle

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The current status of camptothecin analogues as antitumor agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Application of arabinofuranosyl cytosine in the kinetic analysis and quantitation of DNA repair in human cells after ultraviolet irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Rapid kinetics of the interaction between daunomycin and drug-sensitive or drug-resistant P388 leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Comparative cytotoxicities of various morpholinyl anthracyclines.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Proliferation dependence of topoisomerase II mediated drug action

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Purification and characterization of an altered topoisomerase II from a drug-resistant Chinese hamster ovary cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Elevated DNA topoisomerase II activity in nitrogen mustard-resistant human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Altered expression and transcription of the topoisomerase II gene in nitrogen mustard-resistant human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase activities in concanavalin A-stimulated lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA amplification in multidrug, cross-resistant Chinese hamster ovary cells: molecular characterization and cytogenetic localization of the amplified DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Pleiotropic-resistant phenotype is a multifactorial phenomenon in human colon carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Synthesis of adriamycin-coupled polyglutaraldehyde microspheres and evaluation of their cytostatic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The anticancer agent adriamycin can be actively cytotoxic without entering cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Chemosensitisation by verapamil and cyclosporin A in mouse tumour cells expressing different levels of P-glycoprotein and CP22 (sorcin).

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cyclosporins as drug resistance modifiers

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Basis for differential cellular sensitivity to 8-azaguanine and 6-thioguanine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cortisol is transported by the multidrug resistance gene product P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Correction of altered plasma membrane potentials. A possible mechanism of cyclosporin A and verapamil reversal of pleiotropic drug resistance in neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Clinical Relevance of Immunohistochemical Detection of Multidrug Resistance P-Glycoprotein in Breast Carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Processing of psoralen adducts in an active human gene: repair and replication of DNA containing monoadducts and interstrand cross-links

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Direct experimental evidence for competitive inhibition of dihydrofolate reductase by methotrexate.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

1 reference

7 January 2021

Mutator phenotypes in mammalian cell mutants with distinct biochemical defects and abnormal deoxyribonucleoside triphosphate pools

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Formation of DNA-adducts and induction of DNA-crosslinks and chromosomal aberrations by the new potent anthracycline antitumor antibiotics: morpholinodaunomycin, cyanomorpholinodaunomycin and cyanomorpholinoadriamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

P-glycoprotein expression in primary breast cancer detected by immunocytochemistry with two monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA amplification is rare in normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Phospholipid and ether linked phospholipid content alter with cellular resistance to vinblastine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Two-compartment behavior during transport of folate compounds in L1210 cell plasma membrane vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Nucleoside transport and cytosine arabinoside (araC) metabolism in human T lymphoblasts resistant to araC, thymidine and 6-methylmercaptopurine riboside

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Chloroquine enhancement of anticancer drug cytotoxicity in multiple drug resistant human leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

The inhibition in vitro of DNA polymerase and RNA polymerases by daunomycin and adriamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

DNA topoisomerase II as a target of antineoplastic drug therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Folate and anti-folate transport in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Glutathione transferases--structure and catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

Dihydrofolate reductase as a therapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962253-6

7 January 2021

10.1016/S0074-7696(08)62253-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7860220%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference