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English
Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis.
scientific article published on November 2003
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
title
Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
main subject
medulloblastoma
0 references
author name string
Wei Wang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
Robert J B Macaulay
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
publication date
1 November 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
published in
Canadian Journal of Neurological Sciences
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
volume
30
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
page(s)
349-357
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
cites work
A phase I-II trial of lovastatin for anaplastic astrocytoma and glioblastoma multiforme
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
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Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
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Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
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K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
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An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
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Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin-induced E2F-1 modulation and its effect on prostate cancer cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis of medulloblastoma cells in vitro follows inhibition of farnesylation using manumycin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance gene expression in pediatric primitive neuroectodermal tumors of the central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular oncogenes and suppressor genes as prognostic markers in cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
inferred from DOI database lookup
Development of inhibitors of protein farnesylation as potential chemotherapeutic agents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
inferred from DOI database lookup
A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
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7 January 2021
based on heuristic
inferred from DOI database lookup
Promotion and inhibition of activation-induced apoptosis in T-cell hybridomas by oncogenes and related signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of mammalian G1 cyclin-dependent kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: lovastatin specifically targets P-glycoprotein-expressing cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term effects of radiation for medulloblastoma on intellectual and physical development. A case report of monozygotic twins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in fibroblasts by c-myc protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin potentiates antitumor activity of doxorubicin in murine melanoma via an apoptosis-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediation of c-Myc-induced apoptosis by p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid and substantial lowering of human serum cholesterol by mevinolin (MK-803), an inhibitor of hydroxymethylglutaryl-coenzyme A reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control of p27Kip1 accumulation during the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surveillance scanning of children with medulloblastoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of RAS mRNA level by the mevalonate pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Medulloblastoma: I. Clinical, diagnostic, and therapeutic overview
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primitive neuroectodermal tumors of the central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer cell cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53 tumour suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of dexamethasone and lovastatin (mevinolin) as growth inhibitors in cultures of T-cell derived human acute leukemia lines (CEM).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-IgM-mediated regulation of c-myc and its possible relationship to apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ras genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mevalonate prevents lovastatin-induced apoptosis in medulloblastoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of p53-dependent apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100003061
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1017/S0317167100003061
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
PubMed publication ID
14672267
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14672267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672267%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
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