(Q40613613)

22 September 2017

title

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding (English)

1 reference

22 September 2017

4

Judith Frydman

1 reference

22 September 2017

Douglas E Feldman

1

1 reference

22 September 2017

Christoph Spiess

series ordinal

2

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22 September 2017

Daniel E Howard

series ordinal

3

1 reference

22 September 2017

publication date

1 November 2003

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22 September 2017

1 reference

22 September 2017

volume

12

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22 September 2017

issue

5

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22 September 2017

page(s)

1213-1224

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Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Software and database for the analysis of mutations in the VHL gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

The Hsp70 and Hsp60 chaperone machines

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7 January 2021

Thermodynamic stability of wild-type and mutant p53 core domain

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7 January 2021

The CCT chaperonin promotes activation of the anaphase-promoting complex through the generation of functional Cdc20.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Von Hippel-Lindau disease: clinical and molecular perspectives

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7 January 2021

The structural basis of protein folding and its links with human disease

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Inhibition of transcription elongation by the VHL tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Macromolecular crowding: an important but neglected aspect of the intracellular environment

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7 January 2021

Multivalent binding of nonnative substrate proteins by the chaperonin GroEL.

1 reference

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7 January 2021

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

1 reference

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7 January 2021

Folding of newly translated proteins in vivo: the role of molecular chaperones

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7 January 2021

Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms

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7 January 2021

Functional organization of the yeast proteome by systematic analysis of protein complexes

1 reference

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7 January 2021

Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Molecular chaperones in the cytosol: from nascent chain to folded protein

1 reference

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7 January 2021

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

1 reference

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7 January 2021

Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin

1 reference

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7 January 2021

Molecular basis of the VHL hereditary cancer syndrome

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7 January 2021

Protein folding: versatility of the cytosolic chaperonin TRiC/CCT.

1 reference

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7 January 2021

Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations

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7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Mutational screen identifies critical amino acid residues of beta-actin mediating interaction between its folding intermediates and eukaryotic cytosolic chaperonin CCT.

1 reference

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7 January 2021

The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

1 reference

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7 January 2021

Crystal structure of the CCTgamma apical domain: implications for substrate binding to the eukaryotic cytosolic chaperonin

1 reference

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7 January 2021

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

1 reference

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7 January 2021

Contact order, transition state placement and the refolding rates of single domain proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

From computer simulations to human disease: emerging themes in protein folding

1 reference

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7 January 2021

Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

The WD repeat: a common architecture for diverse functions

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

In vivo newly translated polypeptides are sequestered in a protected folding environment

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900423-4

7 January 2021

10.1016/S1097-2765(03)00423-4

Identifiers

DOI

1 reference

22 September 2017

1 reference