(Q40623717)

22 September 2017

Gene Expression Profiling in Ataxin-3 Expressing Cell Lines Reveals Distinct Effects of Normal and Mutant Ataxin-3 (English)

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

24 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

24 March 2024

8

Ullrich Wüllner

1 reference

22 September 2017

7

Thomas Klockgether

1 reference

22 September 2017

Lucia Ozimek

4

1 reference

22 September 2017

Bernd O. Evert

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

Ina R. Vogt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

Ana M. Vieira-Saecker

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

Rob A. I. de Vos

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

Ewout R. P. Brunt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

24 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14575237

24 March 2024

publication date

1 October 2003

1 reference

full work available at URL

22 September 2017

https://academic.oup.com/jnen/article-pdf/62/10/1006/9553022/62-10-1006.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

http://apt.allenpress.com/aptonline/?request=get-abstract&issn=0022-3069&volume=062&issue=10&page=1006

24 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14575237

Journal of Neuropathology & Experimental Neurology

24 March 2024

published in

1 reference

22 September 2017

62

1 reference

22 September 2017

10

1 reference

22 September 2017

1006-1018

1 reference

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

22 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

An isoform of ataxin-3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Toward an understanding of polyglutamine neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Glutamine repeats and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

High density synthetic oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Biological role of the CCAAT/enhancer-binding protein family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Calcium regulation of neuronal gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Identification of a signaling pathway involved in calcium regulation of BDNF expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

A model for the quaternary structure of the proteasome activator PA28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine protein aggregation and toxicity are linked to the cellular stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Positive and negative transcriptional elements of the human type IV collagenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.10.1006

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

21 January 2018

10

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease

24 March 2024

11

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains

24 March 2024

20

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Cell-cell interaction and tissue factor expression

24 March 2024

26

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway

24 March 2024

38

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

A clinical and pathologic study of a large Japanese family with Machado-Joseph disease tightly linked to the DNA markers on chromosome 14q

24 March 2024

41

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

A critical role for the proteasome activator PA28 in the Hsp90-dependent protein refolding

24 March 2024

49

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

24 March 2024

51

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

24 March 2024

57

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation

24 March 2024

58

1 reference

https://api.crossref.org/works/10.1093/JNEN/62.10.1006

24 March 2024

Identifiers

1 reference

22 September 2017

1 reference