(Q33891342)

29 July 2017

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title

Toward an understanding of polyglutamine neurodegeneration (English)

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29 July 2017

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Paulson HL

1

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29 July 2017

publication date

1 April 2000

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29 July 2017

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29 July 2017

volume

10

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29 July 2017

issue

2

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29 July 2017

page(s)

293-299

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Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

21 January 2018

1 reference

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

21 January 2018

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Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

21 January 2018

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High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells

21 January 2018

1 reference

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Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

21 January 2018

1 reference

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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

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Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer's disease and spinocerebellar ataxia 2.

21 January 2018

1 reference

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Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

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Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo

21 January 2018

1 reference

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Abundant expression and cytoplasmic aggregations of [alpha]1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6

21 January 2018

1 reference

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Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

21 January 2018

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Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

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Expanding our understanding of polyglutamine diseases through mouse models

21 January 2018

1 reference

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

21 January 2018

1 reference

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Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Glutamine repeats and neurodegenerative diseases: molecular aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

1 reference

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Recent advances in understanding the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2000.TB00263.X

10.1111/J.1750-3639.2000.TB00263.X

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference