(Q40625542)

22 September 2017

title

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin (English)

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22 September 2017

3

Matthew D Scharff

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22 September 2017

Caroline J Woo

1

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22 September 2017

Alberto Martin

series ordinal

2

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22 September 2017

language of work or name

English

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publication date

1 October 2003

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22 September 2017

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22 September 2017

volume

19

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22 September 2017

issue

4

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22 September 2017

page(s)

479-489

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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

22 September 2017

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Increased transcription levels induce higher mutation rates in a hypermutating cell line

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Histone modifications in transcriptional regulation

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7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

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DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

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ChIPs of the beta-globin locus: unraveling gene regulation within an active domain

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Genomic instability in mice lacking histone H2AX

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7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

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7 January 2021

Stepwise activation of the immunoglobulin mu heavy chain gene locus

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7 January 2021

Induction of somatic mutation in a human B cell line in vitro

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7 January 2021

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

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7 January 2021

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

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7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription

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Activation of p53 in MDM2-overexpressing cells through phosphorylation

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Translating the Histone Code

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7 January 2021

Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development

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7 January 2021

Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation

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7 January 2021

Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

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7 January 2021

Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression

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7 January 2021

Chromatin remodeling at the Ig loci prior to V(D)J recombination

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7 January 2021

Somatic hypermutation: how many mechanisms diversify V region sequences?

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7 January 2021

Somatic hypermutation of the AID transgene in B and non-B cells

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7 January 2021

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

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7 January 2021

A role for histone acetylation in the developmental regulation of VDJ recombination.

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7 January 2021

Effects of Sequence and Structure on the Hypermutability of Immunoglobulin Genes

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7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

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7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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7 January 2021

Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

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7 January 2021

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

1 reference

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7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

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7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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7 January 2021

In vivo and in vitro studies of immunoglobulin gene somatic hypermutation

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7 January 2021

Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus.

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7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

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7 January 2021

Molecular aspects of somatic hypermutation of immunoglobulin genes

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7 January 2021

Somatic hypermutation of immunoglobulin and non-immunoglobulin genes

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7 January 2021

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

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7 January 2021

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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7 January 2021

Variability in the Lambda Light Chain Sequences of Mouse Antibody

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7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

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7 January 2021

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Identifiers

DOI

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22 September 2017

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