(Q40631358)

English

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

scientific article published on September 1, 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration (English)

1 reference

Europe PubMed Central

22 September 2017

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration (English)

1 reference

10.1046/J.1460-9568.2003.02864.X

https://api.crossref.org/works/10.1046/J.1460-9568.2003.02864.X

14 March 2024

apoptotic process

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1 reference

based on heuristic

inferred from title

1 reference

ChEBI release 2020-05-28

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based on heuristic

inferred from title

Masashi Kitazawa

3

object named as

Masashi Kitazawa

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14511319

14 March 2024

author name string

Siddharth Kaul

1

1 reference

Europe PubMed Central

22 September 2017

Arthi Kanthasamy

2

1 reference

Europe PubMed Central

22 September 2017

Vellareddy Anantharam

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1 reference

Europe PubMed Central

22 September 2017

Anumantha G. Kanthasamy

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14511319

14 March 2024

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1 September 2003

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Europe PubMed Central

22 September 2017

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1460-9568.2003.02864.x

1 reference

10.1046/J.1460-9568.2003.02864.X

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https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1460-9568.2003.02864.x

1 reference

10.1046/J.1460-9568.2003.02864.X

https://api.crossref.org/works/10.1046/J.1460-9568.2003.02864.X

14 March 2024

European Journal of Neuroscience

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Europe PubMed Central

22 September 2017

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22 September 2017

1387-1401

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Europe PubMed Central

22 September 2017

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Europe PubMed Central

22 September 2017

Characterization of hydrogen peroxide toxicity in cultured rat forebrain neurons.

1 reference

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The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Calpha

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Histone H2B phosphorylation in mammalian apoptotic cells. An association with DNA fragmentation

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Chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to monkeys: behavioural, morphological and biochemical correlates.

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Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.

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Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism

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Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

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The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease

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Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease

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The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.

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Role of nuclear PKC delta in mediating caspase-3-upregulation in Jurkat T leukemic cells exposed to ionizing radiation

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Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis

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Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblasts

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Caspases: the executioners of apoptosis

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PKC-δ is an apoptotic lamin kinase

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Protein kinase C isozymes and the regulation of diverse cell responses

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Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence

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Protein kinase C-epsilon promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway

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Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons.

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

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Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells

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Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

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Metabolism of the neurotoxin in MPTP by human liver monoamine oxidase B.

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

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Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells

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Protein kinase C delta

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Survival and proliferation of cells expressing caspase-uncleavable Poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent

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Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

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Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.

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Identifiers

10.1046/J.1460-9568.2003.02864.X

1 reference

Europe PubMed Central

22 September 2017

1 reference

Europe PubMed Central

22 September 2017

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