(Q40634782)

22 September 2017

Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression (English)

1 reference

22 September 2017

5

1 reference

22 September 2017

Lidija Klampfer

1

1 reference

22 September 2017

Jie Huang

2

1 reference

22 September 2017

Georgia Corner

3

1 reference

22 September 2017

John Mariadason

4

1 reference

22 September 2017

Takehiko Sasazuki

6

1 reference

22 September 2017

Senji Shirasawa

7

1 reference

22 September 2017

Leonard Augenlicht

8

1 reference

22 September 2017

language of work or name

English

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publication date

12 September 2003

1 reference

Journal of Biological Chemistry

22 September 2017

1 reference

22 September 2017

278

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22 September 2017

47

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22 September 2017

46278-46287

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Lessons from hereditary colorectal cancer

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

A genome-wide survey of RAS transformation targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Signaling through the JAK/STAT pathway, recent advances and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

ISGF3 gamma p48, a specificity switch for interferon activated transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Stat1-independent regulation of gene expression in response to IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Biologic consequences of Stat1-independent IFN signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Interferon (I): on the threshold of clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Chronic myeloid leukemia cells resistant to interferon-alpha lack STAT1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Complex roles of Stat1 in regulating gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

A weak signal for strong responses: interferon-alpha/beta revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Constitutive IFN-alpha/beta signal for efficient IFN-alpha/beta gene induction by virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Multiple levels of MHC class I down-regulation by ras oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Selective loss of beta 2-microglobulin mRNA in human colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Rescue of Daudi cell HLA expression by transfection of the mouse beta 2-microglobulin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

The roles of IFN gamma in protection against tumor development and cancer immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Activation of STAT proteins and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Effects of adenovirus E1A protein on interferon-signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Direct suppression of Stat1 function during adenoviral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Novel functions of interferon-induced proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

IRF-1 reverts the transformed phenotype of oncogenically transformed cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Stat protein transactivation domains recruit p300/CBP through widely divergent sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

21 January 2018

Preface: STAT signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Interferon: no magic bullet against cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304721200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304721200

1 reference

22 September 2017

1 reference