(Q40637908)

English

Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding sta

scientific article published on 3 September 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding sta (English)

1 reference

Europe PubMed Central

22 September 2017

transmembrane protein

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multiple drug resistance

1 reference

based on heuristic

inferred from title

6

object named as

Roger G Deeley

1 reference

Europe PubMed Central

22 September 2017

author name string

Da-Wei Zhang

1

1 reference

Europe PubMed Central

22 September 2017

Hong-Mei Gu

2

1 reference

Europe PubMed Central

22 September 2017

Donna Situ

3

1 reference

Europe PubMed Central

22 September 2017

Anass Haimeur

4

1 reference

Europe PubMed Central

22 September 2017

Susan P C Cole

5

1 reference

Europe PubMed Central

22 September 2017

language of work or name

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publication date

3 September 2003

1 reference

Europe PubMed Central

22 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

22 September 2017

278

1 reference

Europe PubMed Central

22 September 2017

46

1 reference

Europe PubMed Central

22 September 2017

46052-46063

1 reference

Europe PubMed Central

22 September 2017

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Significance of multi-drug-resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

cDNA cloning and genomic organization of the murine MRP7, a new ATP-binding cassette transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Membrane topology and glycosylation of the human multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Functional analysis of MRP1 cloned from bovine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

ATP binding, not hydrolysis, at the first nucleotide-binding domain of multidrug resistance-associated protein MRP1 enhances ADP.Vi trapping at the second domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308403200

21 January 2018

Identifiers

10.1074/JBC.M308403200

1 reference

Europe PubMed Central

22 September 2017

1 reference

Europe PubMed Central

22 September 2017

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