(Q40653726)

English

Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.

scientific article published on April 2003

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

(E)-guggulsterone

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Erika Owsley

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 April 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Biochemical and Biophysical Research Communications

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

304

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2 November 2019

1

1 reference

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2 November 2019

191-195

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Bile acid regulation of gene expression: roles of nuclear hormone receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

A natural product that lowers cholesterol as an antagonist ligand for FXR.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Identification of gene-selective modulators of the bile acid receptor FXR.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900551-5

7 January 2021

Identifiers

10.1016/S0006-291X(03)00551-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705905%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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