(Q40655513)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays (English)

1 reference

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2 November 2019

2

1 reference

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2 November 2019

Anne-Marie Le Bon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Marie-Christine Chagnon

5

object named as

Marie-Christine Chagnon

1 reference

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2 November 2019

author name string

Isabelle Valentin-Severin

1

1 reference

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2 November 2019

Jean-Claude Lhuguenot

3

1 reference

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2 November 2019

language of work or name

English

0 references

publication date

1 April 2003

1 reference

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2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

79-90

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

The effectiveness of S9 and microsomal mix on activation of cyclophosphamide to induce genotoxicity in human lymphocytes

2 November 2019

cites work

1 reference

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7 January 2021

Limitations of metabolic activation systems used with in vitro tests for carcinogens

1 reference

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7 January 2021

Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells

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7 January 2021

Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

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7 January 2021

Human hepatocytes in genotoxicity assays

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7 January 2021

Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes

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7 January 2021

Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells.

1 reference

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7 January 2021

Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens

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7 January 2021

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

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7 January 2021

Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

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7 January 2021

Metabolic activation of benzo[a]pyrene by a human hepatoma cell line.

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7 January 2021

Drug metabolism by the human hepatoma cell, Hep G2

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7 January 2021

Single cell gel electrophoresis assay: a new technique for human biomonitoring studies

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7 January 2021

The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations

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7 January 2021

The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

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7 January 2021

The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program

1 reference

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7 January 2021

Measurement of micronuclei in lymphocytes

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7 January 2021

Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromer

1 reference

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7 January 2021

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

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7 January 2021

The single cell gel electrophoresis assay (comet assay): a European review

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7 January 2021

Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells

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7 January 2021

A simple technique for quantitation of low levels of DNA damage in individual cells

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7 January 2021

Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay.

1 reference

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7 January 2021

The nature and origin of DNA single-strand breaks determined with the comet assay

1 reference

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7 January 2021

Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells

1 reference

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7 January 2021

In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells

1 reference

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7 January 2021

The ability of the Comet assay to discriminate between genotoxins and cytotoxins

1 reference

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7 January 2021

Uridine uptake inhibition as a cytotoxicity test for a human hepatoma cell line (HepG2 cells): comparison with the neutral red assay

1 reference

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7 January 2021

Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens

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7 January 2021

Uridine uptake inhibition assay: an automated micromethod for the screening of cytotoxicity

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7 January 2021

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

1 reference

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7 January 2021

The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes

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7 January 2021

Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin

1 reference

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7 January 2021

Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions

1 reference

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7 January 2021

Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt–tungsten carbide

1 reference

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7 January 2021

In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: a structure-activity relation

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7 January 2021

Heterocyclic aromatic amines induce DNA strand breaks and cell transformation

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7 January 2021

Use of the alkaline comet assay for industrial genotoxicity screening: comparative investigation with the micronucleus test.

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7 January 2021

Comparison of DNA-repair synthesis, chromosome aberrations and induction of micronuclei in cultured human fibroblasts, Chinese hamster ovary and central mudminnow (Umbra limi) cells exposed to chemical mutagens

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7 January 2021

Detection of DNA lesions induced by chemical mutagens using the single-cell gel electrophoresis (comet) assay. 2. Relationship between DNA migration and alkaline condition

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7 January 2021

Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells

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7 January 2021

Expression of Cytochromes P-450 2E1, 3A4 and 1A1/1A2 in Growing and Confluent Human HepG2 Hepatoma Cells-Effect of Ethanol

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7 January 2021

Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR.

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7 January 2021

N-nitrosamines: bacterial mutagenesis and in vitro metabolism

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7 January 2021

Enhanced mutagenic activities of N-nitroso compounds in weakly acidic media.

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7 January 2021

Genotoxic activity and potency of 135 compounds in the Ames reversion test and in a bacterial DNA-repair test

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7 January 2021

Analysis of rat lymphocyte activation of benzo[a]pyrene, 2-acetylaminofluorene, and several of their metabolites to mutagenic and DNA-damaging species in vitro

1 reference

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7 January 2021

10.1016/S1383-5718(03)00031-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694748%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference