(Q40657727)

22 September 2017

title

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK. (English)

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22 September 2017

6

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22 September 2017

E Tamagno

1

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22 September 2017

G Robino

2

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22 September 2017

A Obbili

3

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22 September 2017

P Bardini

4

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22 September 2017

M Aragno

5

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22 September 2017

O Danni

7

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22 September 2017

language of work or name

English

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publication date

1 April 2003

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22 September 2017

published in

Experimental Neurology

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22 September 2017

volume

180

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22 September 2017

issue

2

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22 September 2017

page(s)

144-155

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Vitamin E protects nerve cells from amyloid beta protein toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Hydrogen peroxide mediates amyloid beta protein toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Oxidative stress and Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Relative contribution of different receptor subtypes in the response of neuroblastoma cells to tumor necrosis factor-alpha.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Possible involvement of the lipid-peroxidation product 4-hydroxynonenal in the formation of fluorescent chromolipids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Oxidative stress as a regulator of gene expression in the vasculature

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Biphasic modulation of protein kinase C and enhanced cell toxicity by amyloid beta peptide and anoxia in neuronal cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Neurodegenerative disorders and ischemic brain diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

HNE interacts directly with JNK isoforms in human hepatic stellate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Oxidative damage and fibrogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

The presence, origin, and significance of A beta peptide in the cell bodies of neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Alzheimer's disease: genes, proteins, and therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

JNK activation is associated with intracellular beta-amyloid accumulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

NT2 neurons, a classical model for Alzheimer's disease, are highly susceptible to oxidative stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Rho family members: activators of MAP kinase cascades.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Interleukin-1beta induction of mitogen-activated protein kinases in human mesangial cells. Role of oxidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Identification of an NADH plus iron dependent, Ca2+ activated hydrogen peroxide production in synaptosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

Oxidative alterations in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2802%2900059-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-4886(02)00059-6

1 reference

22 September 2017

1 reference