(Q33546151)

27 July 2017

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title

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches (English)

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27 July 2017

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Behl C

1

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27 July 2017

1 February 1999

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27 July 2017

Progress in Neurobiology

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27 July 2017

57

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27 July 2017

301-323

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27 July 2017

3

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Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

27 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Transgenic and knockout mice in the study of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Inflammation and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Inflammatory mechanisms in Alzheimer's disease: implications for therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Glucocorticoids in Alzheimer's disease. The story so far.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Brain microglia constitutively express beta-2 integrins.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Role of metals in oxygen radical reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Activate NF-kappa B or die?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Evidence of an oxidative challenge in the Alzheimer's brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyloid beta-protein toxicity and oxidative stress in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Vitamin E protects nerve cells from amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyloid beta peptide induces necrosis rather than apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Protection against oxidative stress-induced neuronal cell death--a novel role for RU486.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neuroprotection against oxidative stress by estrogens: structure-activity relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Demonstration of Amyloid Deposits and Neurofibrillary Changes in Whole Brain Sections

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Normal host prion protein necessary for scrapie-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Distribution of cerebral degeneration in Alzheimer's disease. A clinico-pathological study

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Limbic lobe involvement in presenile dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neuroprotection by antioxidants in models of global and focal ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Implants containing beta-amyloid protein are not neurotoxic to young and old rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Enzymic mechanisms of superoxide production

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

X-ray diffraction studies on amyloid filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Oxidative stress and antioxidant therapy in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The role of complement and activated microglia in the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

A beta deposition inhibitor screen using synthetic amyloid.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Effects of chronic infusion of nerve growth factor (NGF) in AF64A-lesioned rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Effects of injected Alzheimer beta-amyloid cores in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The Biology of Oxygen Radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Involvement of free oxygen radicals in beta-amyloidosis: an hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Lack of Alzheimer pathology after beta-amyloid protein injections in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Differential effects of amyloid peptides beta-(1-40) and beta-(25-35) injections into the rat nucleus basalis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Alzheimer's disease: its proteins and genes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

17 alpha-estradiol exerts neuroprotective effects on SK-N-SH cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Estrogen receptor beta--getting in on the action?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Presenilins: genes for life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochemical study using a novel monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Brain membrane fluidity and lipid peroxidation in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

New insights into the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Free Radical Theory of Aging: Inhibition of Amyloidosis in Mice by Antioxidants; Possible Mechanism*

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Transgenic mouse brain histopathology resembles early Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Senile dementia-Alzheimer's type and estrogen

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Age as risk factor for sporadic dementia of the Alzheimer type?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Brain glucose metabolism is controlled by amplification and desensitization of the neuronal insulin receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The toxicity in vitro of beta-amyloid protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Potential involvement of the transcription factor NF-kappa B in neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Diagnosis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Early amyloid-beta deposits show different immunoreactivity to the amino- and carboxy-terminal regions of beta-peptide in Alzheimer's disease and Down's syndrome brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Brain glutathione peroxidase in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Making models for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neuroprotection by anti-oxidant strategies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Transcription factor NF-kappaB: friend or foe of neurons?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Melatonin prevents oxidative stress-induced cell death in hippocampal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Janus faces of NF-kappa B: neurodestruction versus neuroprotection

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Oxygen radicals and neuropsychiatric illness. Some speculations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Kinetic theory of fibrillogenesis of amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neurocytopathic effects of beta-amyloid-stimulated monocytes: a potential mechanism for central nervous system damage in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

The neuropathology of Alzheimer's disease: a review with pathogenetic, aetiological and therapeutic considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Oxidative stress hypothesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Superoxide dismutase isoenzymes in normal brains and in brains from patients with dementia of Alzheimer type.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Neurotoxicity of human amylin in rat primary hippocampal cultures: similarity to Alzheimer's disease amyloid-beta neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2898%2900055-0

7 January 2021

Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease.

1 reference

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7 January 2021

Non-genomic and genomic effects of steroids on neural activity

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7 January 2021

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

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7 January 2021

The role of the immune system in neurodegenerative disorders

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7 January 2021

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

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7 January 2021

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

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7 January 2021

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

1 reference

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7 January 2021

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

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7 January 2021

Decreases in protective enzymes correlates with increased oxidative damage in the aging mouse brain.

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7 January 2021

Estrogen blocks neurotoxic effects of beta-amyloid (1-42) and induces neurite extension on B103 cells

1 reference

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7 January 2021

Neuroprotective potential of aromatic alcohols against oxidative cell death

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7 January 2021

1 reference

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7 January 2021

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

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7 January 2021

Effects of growth factors and estrogen on the development of septal cholinergic neurons from the rat.

1 reference

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7 January 2021

Peroxynitrite: a two-faced metabolite of nitric oxide

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7 January 2021

Genetic and molecular advances in Alzheimer's disease

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7 January 2021

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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7 January 2021

Novel and potent biological antioxidants on membrane phospholipid peroxidation: 2-hydroxy estrone and 2-hydroxy estradiol

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7 January 2021

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

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7 January 2021

Evidence for a membrane defect in Alzheimer disease brain

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7 January 2021

The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro

1 reference

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7 January 2021

A radical hypothesis for neurodegeneration

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7 January 2021

Estrogen deficiency and risk of Alzheimer's disease in women.

1 reference

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7 January 2021

The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis

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7 January 2021

Antioxidant: a new role for RU-486 and related compounds

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7 January 2021

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

1 reference

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7 January 2021

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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7 January 2021

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

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7 January 2021

Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress.

1 reference

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7 January 2021

New perspectives on Alzheimer's disease

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7 January 2021

Novel proteinaceous infectious particles cause scrapie

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7 January 2021

Molecular biology and pathogenesis of prion diseases

1 reference

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7 January 2021

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

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7 January 2021

Functional pleiotropy of the neurohormone melatonin: antioxidant protection and neuroendocrine regulation

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7 January 2021

Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

1 reference

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7 January 2021

The inhibition of low-density lipoprotein oxidation by 17-beta estradiol

1 reference

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7 January 2021

Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group.

1 reference

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7 January 2021

Complement activation by beta-amyloid in Alzheimer disease

1 reference

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7 January 2021

Clinical trial of indomethacin in Alzheimer's disease.

1 reference

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7 January 2021

Beta-amyloid from Alzheimer disease brains inhibits sprouting and survival of sympathetic neurons.

1 reference

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7 January 2021

Apolipoprotein E, a gene with complex biological interactions in the aging brain

1 reference

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7 January 2021

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

1 reference

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7 January 2021

The neuropsychopharmacological potential of neuroactive steroids

1 reference

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7 January 2021

Increased antioxidant enzyme activity in amyloid beta protein-resistant cells

1 reference

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7 January 2021

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

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7 January 2021

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

1 reference

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7 January 2021

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

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7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

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7 January 2021

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

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7 January 2021

The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix

1 reference

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7 January 2021

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

1 reference

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7 January 2021

Amyloid peptides are toxic via a common oxidative mechanism

1 reference

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7 January 2021

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

1 reference

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7 January 2021

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

1 reference

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7 January 2021

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

1 reference

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7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

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7 January 2021

Neurodegenerative disease. Oxidative stress and motorneuron disease.

1 reference

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7 January 2021

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

1 reference

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7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

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7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

1 reference

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7 January 2021

Strategies of antioxidant defense

1 reference

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7 January 2021

The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease.

1 reference

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7 January 2021

Flauoprotein structure and mechanism 2. Monoamine oxidases: old friends hold many surprises.

1 reference

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7 January 2021

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

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7 January 2021

Role of the beta-amyloid protein in Alzheimer's disease.

1 reference

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7 January 2021

Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease

1 reference

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7 January 2021

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

1 reference

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7 January 2021

Tau protein directly interacts with the amyloid beta-protein precursor: implications for Alzheimer's disease.

1 reference

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7 January 2021

Radical AGEing in Alzheimer's disease

1 reference

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7 January 2021

1 reference

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7 January 2021

Oxidative damage in Alzheimer's.

1 reference

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7 January 2021

An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

1 reference

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7 January 2021

Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease

1 reference

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7 January 2021

Apolipoprotein E and Alzheimer disease

1 reference

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7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

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7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

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7 January 2021

Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro

1 reference

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7 January 2021

Estrogens as natural antioxidants of membrane phospholipid peroxidation

1 reference

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

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7 January 2021

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease.

1 reference

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7 January 2021

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

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7 January 2021

The gene defects responsible for familial Alzheimer's disease

1 reference

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7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

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7 January 2021

Neurotrophins and neuronal plasticity

1 reference

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7 January 2021

Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease.

1 reference

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7 January 2021

Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain

1 reference

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7 January 2021

Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta

1 reference

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7 January 2021

Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain

1 reference

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7 January 2021

Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labeling immunohistochemical study.

1 reference

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7 January 2021

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

1 reference

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7 January 2021

17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors.

1 reference

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7 January 2021

Enhanced aggregation and beta structure of amyloid beta peptide after coincubation with C1q.

1 reference

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7 January 2021

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

1 reference

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7 January 2021

Biochemistry and genetics of monoamine oxidase

1 reference

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7 January 2021

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

1 reference

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7 January 2021

Lack of long-term effects after beta-amyloid protein injections in rat brain

1 reference

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7 January 2021

Essential role of neocortical acetylcholine in spatial memory

1 reference

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7 January 2021

Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor

1 reference

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7 January 2021

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

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7 January 2021

Biology of A beta amyloid in Alzheimer's disease

1 reference

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7 January 2021

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

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7 January 2021

A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining.

1 reference

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7 January 2021

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

1 reference

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7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

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7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

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7 January 2021

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

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7 January 2021

Nerve growth factor potentiates the neurotoxicity of beta amyloid

1 reference

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7 January 2021

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor.

1 reference

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7 January 2021

An in vitro EPR study of the free-radical scavenging actions of the lazaroid antioxidants U-74500A and U-78517F.

1 reference

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7 January 2021

10.1016/S0301-0082(98)00055-0

Identifiers

DOI

1 reference

release_elp5r5h5dzek3e5cthcb4mkuma

27 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/elp5r5h5dzek3e5cthcb4mkuma

24 November 2022

mapped directly with Wikidata item

PubMed ID

10096843

1 reference

PubMed ID

10096843