(Q40662629)

English

Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts

scientific article published on 18 March 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Shailaja Uttamsingh

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Cong S Zong

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Lu-Hai Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

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publication date

18 March 2003

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

number of pages

13

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

18798-18810

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Characterization of ROS1 cDNA from a human glioblastoma cell line

1 reference

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21 January 2018

The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis

1 reference

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21 January 2018

Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression

1 reference

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21 January 2018

Mutations of Ros differentially effecting signal transduction pathways leading to cell growth versus transformation

1 reference

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21 January 2018

Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

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21 January 2018

Anchorage-dependent cell cycle progression

1 reference

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21 January 2018

Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression.

1 reference

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21 January 2018

The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors.

1 reference

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21 January 2018

Complexity and specificity of integrin signalling.

1 reference

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21 January 2018

Integrins, oncogenes, and anchorage independence.

1 reference

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21 January 2018

Role of cell shape in growth control

1 reference

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21 January 2018

Disruption of epithelial cell-matrix interactions induces apoptosis

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21 January 2018

The extracellular matrix as a cell survival factor

1 reference

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21 January 2018

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

1 reference

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21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

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21 January 2018

Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation

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21 January 2018

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

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21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

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21 January 2018

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

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21 January 2018

Stat5 is a physiological substrate of the insulin receptor

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21 January 2018

Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation

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21 January 2018

The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

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21 January 2018

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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21 January 2018

STAT proteins: novel molecular targets for cancer drug discovery

1 reference

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21 January 2018

Activation and association of Stat3 with Src in v-Src-transformed cell lines

1 reference

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21 January 2018

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

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21 January 2018

Stat3 activation is required for cellular transformation by v-src

1 reference

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21 January 2018

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211522200

21 January 2018

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211522200

21 January 2018

Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1

1 reference

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21 January 2018

Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein

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21 January 2018

Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211522200

21 January 2018

Anchorage-dependent transcription of the cyclin A gene

1 reference

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21 January 2018

A link between cyclin A expression and adhesion-dependent cell cycle progression

1 reference

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21 January 2018

Rapid transformation of cells by Rous sarcoma virus

1 reference

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21 January 2018

Effect of tyrosine mutations on the kinase activity and transforming potential of an oncogenic human insulin-like growth factor I receptor.

1 reference

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21 January 2018

D-type cyclin-dependent kinase activity in mammalian cells

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21 January 2018

Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb

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Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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The function of GRB2 in linking the insulin receptor to Ras signaling pathways

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21 January 2018

The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation

1 reference

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21 January 2018

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts

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21 January 2018

Signaling through focal adhesion kinase

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IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

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21 January 2018

Modulatory effect of the transmembrane domain of the protein-tyrosine kinase encoded by oncogene ros: biological function and substrate interaction

1 reference

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21 January 2018

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

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21 January 2018

Growth factor activation of MAP kinase requires cell adhesion.

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21 January 2018

Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage-dependent growth is associated with increased cdk2 activity

1 reference

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21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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21 January 2018

Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases

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21 January 2018

Phospholipase C-gamma 1 can induce DNA synthesis by a mechanism independent of its lipase activity

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21 January 2018

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells

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Suppression of anchorage-independent growth of human cancer cell lines by the drs gene

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BPV-4 E8 transforms NIH3T3 cells, up-regulates cyclin A and cyclin A-associated kinase activity and de-regulates expression of the cdk inhibitor p27Kip1.

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Novel revertants of H-ras oncogene-transformed R6-PKC3 cells

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

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21 January 2018

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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Integrins and signal transduction pathways: the road taken

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DNA analysis: new kid on the block

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A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

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Transformation of mammalian cells by constitutively active MAP kinase kinase

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Anchorage-independent activation of mitogen-activated protein kinase through phosphatidylinositol-3 kinase by insulin-like growth factor I

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Identifiers

10.1074/JBC.M211522200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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