(Q40663270)

22 September 2017

title

Allosteric modulation of human P-glycoprotein. Inhibition of transport by preventing substrate translocation and dissociation (English)

1 reference

22 September 2017

Nazli Maki

1

1 reference

22 September 2017

Peter Hafkemeyer

series ordinal

2

1 reference

22 September 2017

Saibal Dey

series ordinal

3

1 reference

22 September 2017

language of work or name

English

0 references

publication date

17 March 2003

1 reference

Journal of Biological Chemistry

22 September 2017

published in

1 reference

22 September 2017

volume

278

1 reference

22 September 2017

issue

20

1 reference

22 September 2017

page(s)

18132-18139

1 reference

Biochemistry of multidrug resistance mediated by the multidrug transporter

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Multidrug resistance transporters and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Chemosensitisation by verapamil and cyclosporin A in mouse tumour cells expressing different levels of P-glycoprotein and CP22 (sorcin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

The multi-drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Reversible labeling of a chemosensitizer binding domain of p-glycoprotein with a novel 1,4-dihydropyridine drug transport inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Allosteric regulation of [3H]vinblastine binding to P-glycoprotein of MCF-7 ADR cells by dexniguldipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Harvey murine sarcoma virus/MDR1 retroviral vectors: efficient virus production and foreign gene transduction using MDR1 as a selectable marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Pharmacologic circumvention of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Multiple and essential Sp1 binding sites in the promoter for transforming growth factor-beta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

ABC Transporters: From Microorganisms to Man

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Drug-stimulated ATPase Activity of Human P-glycoprotein Requires Movement between Transmembrane Segments 6 and 12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Decreased uptake of cyclosporin A by P-glycoprotein (Pgp) expressing CEM leukemic cells and restoration of normal retention by Pgp blockers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Communication between multiple drug binding sites on P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

Secondary and tertiary structure changes of reconstituted P-glycoprotein. A Fourier transform attenuated total reflection infrared spectroscopy analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210413200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210413200

1 reference

release_74j6hi4do5hvbf7knkcryhmrzm

22 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/74j6hi4do5hvbf7knkcryhmrzm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference