(Q40674039)

22 September 2017

title

Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene (English)

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22 September 2017

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10

Gert-Jan B van Ommen

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Peter Hohenstein

object named as

Peter Hohenstein

1

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Riccardo Fodde

object named as

Riccardo Fodde

13

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Peter Devilee

12

object named as

Peter Devilee

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22 September 2017

Lia Molenaar

2

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22 September 2017

Joyce Elsinga

3

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22 September 2017

Hans Morreau

4

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22 September 2017

Heleen van der Klift

5

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22 September 2017

Ada Struijk

6

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22 September 2017

Shantie Jagmohan-Changur

7

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22 September 2017

Ron Smits

8

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22 September 2017

Henk van Kranen

9

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22 September 2017

Cees Cornelisse

11

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22 September 2017

publication date

1 March 2003

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Genes, Chromosomes and Cancer

22 September 2017

published in

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22 September 2017

volume

36

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22 September 2017

issue

3

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22 September 2017

page(s)

273-282

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Role of transforming growth factor beta in human disease

22 September 2017

cites work

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7 January 2021

The DCC gene: structural analysis and mutations in colorectal carcinomas

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7 January 2021

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

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7 January 2021

A genetic model for colorectal tumorigenesis

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7 January 2021

Identification of a chromosome 18q gene that is altered in colorectal cancers

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7 January 2021

Disease model: familial adenomatous polyposis

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7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

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7 January 2021

Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients

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7 January 2021

Nonsense-mediated mRNA decay in health and disease

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7 January 2021

The DCC gene product in cellular differentiation and colorectal tumorigenesis

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7 January 2021

A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.

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7 January 2021

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

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7 January 2021

Serrated route to colorectal cancer: back street or super highway?

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7 January 2021

Evolution of colorectal cancer: change of pace and change of direction.

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7 January 2021

Colorectal carcinoma associated with serrated adenoma--prevalence, histological features, and prognosis

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7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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7 January 2021

Assignment1 of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization

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7 January 2021

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

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7 January 2021

Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.

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7 January 2021

Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity

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7 January 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

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7 January 2021

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

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7 January 2021

The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

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7 January 2021

Identifiers

DOI

10.1002/GCC.10169

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22 September 2017

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