(Q40682699)

22 September 2017

title

Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells (English)

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22 September 2017

Ronald D Snyder

1

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22 September 2017

Peter J Gillies

series ordinal

2

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22 September 2017

publication date

1 January 2002

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Environmental and Molecular Mutagenesis

22 September 2017

published in

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22 September 2017

volume

40

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22 September 2017

issue

4

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22 September 2017

page(s)

266-276

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Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation

22 September 2017

cites work

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7 January 2021

Mode of binding of quercetin to DNA

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7 January 2021

Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives

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7 January 2021

Mutagenic Activity of Quercetin and Related Compounds

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7 January 2021

Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I

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7 January 2021

Genotoxicity of several clinically used topoisomerase II inhibitors

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7 January 2021

Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties

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7 January 2021

Potenial antitumor agents. 28. Deoxyribonucleic acid polyintercalating agents

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7 January 2021

Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships

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7 January 2021

The effect of dietary flavonoids on DNA damage (strand breaks and oxidised pyrimdines) and growth in human cells

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7 January 2021

Synthesis and DNA-binding properties of polyamine analogues

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7 January 2021

Measurement of micronuclei in lymphocytes

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7 January 2021

Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites

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7 January 2021

On the mechanisms of genotoxicity and metabolism of quercetin

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7 January 2021

Flavonoids, a class of natural products of high pharmacological potency

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7 January 2021

Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate

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7 January 2021

Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study

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7 January 2021

Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene

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7 January 2021

DNA topoisomerase II rescue by catalytic inhibitors: a new strategy to improve the antitumor selectivity of etoposide

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7 January 2021

Different modes of anthracycline interaction with topoisomerase II. Separate structures critical for DNA-cleavage, and for overcoming topoisomerase II-related drug resistance.

1 reference

7 January 2021

Catalytic inhibition of DNA topoisomerase IIalpha by sodium azide

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7 January 2021

Dietary flavonoids interact with trace metals and affect metallothionein level in human intestinal cells

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7 January 2021

In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes

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7 January 2021

Cell killing and DNA damage induced in cultured mammalian cells by some tetrahydrobenzopsoralenquinones

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7 January 2021

Inhibition of 7-ethoxycoumarin O-deethylase activity in rat liver microsomes by naturally occurring flavonoids: structure-activity relationships

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7 January 2021

Yeast topoisomerase II is inhibited by etoposide after hydrolyzing the first ATP and before releasing the second ADP

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7 January 2021

Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

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7 January 2021

Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.

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7 January 2021

Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavage

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7 January 2021

Genetic toxicological testing of some plant flavonoids by the micronucleus test

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7 January 2021

Chemical features of flavonols affecting their genotoxicity. Potential implications in their use as therapeutical agents.

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7 January 2021

A review and investigation into the mechanistic basis of the genotoxicity of antihistamines

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7 January 2021

Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay

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7 January 2021

The bleomycin amplification assay in V79 cells predicts frameshift mutagenicity of intercalative agents

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7 January 2021

Enhancement of cytotoxicity and clastogenicity of l-DOPA and dopamine by manganese and copper

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7 January 2021

Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds

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7 January 2021

The action of transition metals on the genotoxicity of simple phenols, phenolic acids and cinnamic acids

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7 January 2021

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

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7 January 2021

Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader

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7 January 2021

Distinct mechanisms of DNA damage in apoptosis induced by quercetin and luteolin

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7 January 2021

Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol

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7 January 2021

Mechanism of oxidative DNA damage induced by quercetin in the presence of Cu(II).

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7 January 2021

Identifiers

DOI

10.1002/EM.10121

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release_tzpj4rt4irawnektofabvfeva4

22 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/tzpj4rt4irawnektofabvfeva4

24 November 2022

mapped directly with Wikidata item

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