(Q40694894)

22 September 2017

title

Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation (English)

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22 September 2017

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Po-Chao Chan

1

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22 September 2017

Chun-Chi Liang

2

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22 September 2017

Kuo-Ching Yu

3

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22 September 2017

Ming-Chen Chang

4

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22 September 2017

William L Ho

5

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22 September 2017

Bor-Huah Chen

6

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22 September 2017

Hong-Chen Chen

7

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22 September 2017

language of work or name

English

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publication date

21 October 2002

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

277

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22 September 2017

issue

52

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22 September 2017

page(s)

50373-50379

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Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Regulation of the cell cycle by focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Focal adhesion kinase promotes phospholipase C-gamma1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Stimulation of tyrosine- and serine-phosphorylation of focal adhesion kinase in mouse 3T3 cells by fibronectin and fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Expression of the c-Met/HGF receptor in human breast carcinoma: correlation with tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

A point mutation in the MET oncogene abrogates metastasis without affecting transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

Cas mediates transcriptional activation of the serum response element by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204691200

21 January 2018

Identifiers

DOI

10.1074/JBC.M204691200

1 reference

22 September 2017

1 reference