(Q40716676)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

1 reference

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Alba Casellas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Anna Pujol

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Fatima Bosch

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

J C Devedjian

1

1 reference

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5 November 2019

M George

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

J Visa

5

1 reference

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5 November 2019

L Gros

7

1 reference

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5 November 2019

language of work or name

English

0 references

publication date

1 March 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

5 November 2019

published in

1 reference

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5 November 2019

volume

105

1 reference

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5 November 2019

issue

6

1 reference

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5 November 2019

page(s)

731-740

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

Disruption of IRS-2 causes type 2 diabetes in mice

5 November 2019

cites work

1 reference

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Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

25 September 2017

1 reference

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Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

25 September 2017

1 reference

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Hyperinsulinemia induces a reversible impairment in insulin receptor function leading to diabetes in the sand rat model of non-insulin-dependent diabetes mellitus

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction.

25 September 2017

1 reference

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Central nervous system and peripheral abnormalities: clues to the understanding of obesity and NIDDM.

25 September 2017

1 reference

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Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research

25 September 2017

1 reference

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Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Molecular and cellular aspects of the insulin-like growth factor I receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Sequence of a placental cDNA encoding the mouse insulin-like growth factor II precursor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Genomic imprinting and the strange case of the insulin-like growth factor II receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Insulin-like growth factors (IGFs): implications for aging

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Changes in the islets of langerhans in the obese Zucker rat

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Functional active receptors for insulin-like growth factors-I (IGF-I) and IGF-II on insulin-, glucagon-, and somatostatin-producing cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Studies in the diabetic mutant mouse. II. Electron microscopy of pancreatic islets

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

The influence of genetic background on the expression of the obese (ob) gene in the mouse

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

The pentose cycle and insulin release in mouse pancreatic islets

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Hyperinsulinemia in transgenic mice carrying multiple copies of the human insulin gene.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Expression of somatomedin/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Exaggerated early insulin release and insulin resistance in a diabetes-prone population: a metabolic comparison of Pima Indians and Caucasians

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Muscle insulin resistance may not be a primary etiological factor in the genetically obese fa/fa rat

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Increased amounts of a high molecular weight insulin-like growth factor II (IGF-II) peptide and IGF-II messenger ribonucleic acid in pancreatic islets of diabetic Goto-Kakizaki rats

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377454

Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells

19 August 2018

1 reference

12 December 2020

Glucose metabolism in transgenic mice containing a chimeric P-enolpyruvate carboxykinase/bovine growth hormone gene

1 reference

12 December 2020

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

1 reference

12 December 2020

Insulin-like growth factor-I at physiological concentrations is a potent inhibitor of insulin secretion

1 reference

12 December 2020

Patients with insulinoma show insulin resistance in the absence of arterial hypertension

1 reference

12 December 2020

Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus

1 reference

12 December 2020

What if Minkowski had been ageusic? An alternative angle on diabetes

1 reference

12 December 2020

Immunohistochemical localization of insulin-like growth factor 1 and 2 in the endocrine pancreas of rat, dog, and man, and their coexistence with classical islet hormones

1 reference

12 December 2020

Interactions of nutrients, insulin-like growth factors (IGFs) and IGF-binding proteins in the regulation of DNA synthesis by isolated fetal rat islets of Langerhans

1 reference

12 December 2020

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes

1 reference

12 December 2020

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

1 reference

12 December 2020

Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice

1 reference

12 December 2020

Comparison of insulin sensitivity in patients with insulinoma and obese Type 2 diabetes mellitus

1 reference

12 December 2020

Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors

1 reference

12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

12 December 2020

Ultrastructural localization of insulin-like growth factor-2 (IGF-2) to the secretory granules of insulin cells: a study in normal and diabetic (GK) rats

1 reference

12 December 2020

Structural changes of pancreatic islets in genetically obese rats

1 reference

12 December 2020

Insulin and multiplication stimulating activity (an insulin-like growth factor) stimulate islet (beta-cell replication in neonatal rat pancreatic monolayer cultures

1 reference

12 December 2020

The type II insulin-like growth factor receptor does not mediate increased DNA synthesis in H-35 hepatoma cells

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI5656

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

10727441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727441%20AND%20SRC:MED&resulttype=core&format=json