(Q40719011)

23 September 2017

title

Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187. (English)

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23 September 2017

Ling Wang

1

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23 September 2017

David A Eastmond

series ordinal

2

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23 September 2017

publication date

1 January 2002

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Environmental and Molecular Mutagenesis

23 September 2017

published in

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23 September 2017

volume

39

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23 September 2017

issue

4

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23 September 2017

page(s)

348-356

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Genotoxicity of 17 gyrase- and four mammalian topoisomerase II-poisons in prokaryotic and eukaryotic test systems

23 September 2017

cites work

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DNA topoisomerase II: a review of its involvement in chromosome structure, DNA replication, transcription and mitosis

21 January 2018

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Mutagenic properties of topoisomerase-targeted drugs.

21 January 2018

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Detection of hydroquinone-induced nonrandom breakage in the centromeric heterochromatin of mouse bone marrow cells using multicolor fluorescence in situ hybridization with the mouse major and minor satellite probes

21 January 2018

1 reference

A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

21 January 2018

1 reference

Kinetochore localization in micronucleated cytokinesis-blocked Chinese hamster ovary cells: a new and rapid assay for identifying aneuploidy-inducing agents

21 January 2018

1 reference

Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody.

21 January 2018

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Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

21 January 2018

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Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis

21 January 2018

1 reference

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide

21 January 2018

1 reference

Statistical analyses for in vitro cytogenetic assays using Chinese hamster ovary cells.

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase

21 January 2018

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Inhibitors of topoisomerase II delay progress through mitosis and induce a doubling of the DNA content in CHO cells

21 January 2018

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Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts.

21 January 2018

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Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

21 January 2018

1 reference

Bis(2,6-dioxopiperazines), catalytic inhibitors of DNA topoisomerase II, as molecular probes, cardioprotectors and antitumor drugs

21 January 2018

1 reference

Catalytic inhibitors of DNA topoisomerase II

21 January 2018

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Genotoxicity of several clinically used topoisomerase II inhibitors

21 January 2018

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Apoptosis and the cell cycle: the p53 connection

21 January 2018

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Initial mechanistic studies with merbarone (NSC 336628)

21 January 2018

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Necrosis, apoptosis, cytostasis and DNA damage in human lymphocytes measured simultaneously within the cytokinesis-block micronucleus assay: description of the method and results for hydrogen peroxide

21 January 2018

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Fragmentation of centromeric DNA and prevention of homologous chromosome separation in male mouse meiosis in vivo by the topoisomerase II inhibitor etoposide

21 January 2018

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Effects of the DNA topoisomerase II inhibitor merbarone in male mouse meiotic divisions in vivo: cell cycle arrest and induction of aneuploidy

21 January 2018

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The involvement of chromatin condensation in camptothecin-induced chromosome breaks in G0 human lymphocytes

21 January 2018

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Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16)

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/EM.10072

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23 September 2017

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