(Q40729421)

23 September 2017

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3. (English)

1 reference

23 September 2017

20

1 reference

23 September 2017

22

Michael S Diamond

0 references

Huy-Dung Hoang

Huy-Dung Hoang

7

0 references

Kristy J Szretter

Kristy J Szretter

3

0 references

Jonathan G Pol

Jonathan G Pol

5

0 references

Ali A Ashkar

Ali A Ashkar

17

0 references

Nahum Sonenberg

24

Nahum Sonenberg

1 reference

23 September 2017

23

Karen Mossman

1 reference

23 September 2017

15

Mehul S Suthar

1 reference

23 September 2017

Fuan Wang

1

1 reference

23 September 2017

Tommy Alain

2

1 reference

23 September 2017

Kyle Stephenson

4

1 reference

23 September 2017

Matthew J Atherton

6

1 reference

23 September 2017

Bruno D Fonseca

8

1 reference

23 September 2017

Chadi Zakaria

9

1 reference

23 September 2017

Lan Chen

10

1 reference

23 September 2017

Zainab Rangwala

11

1 reference

23 September 2017

Adam Hesch

12

1 reference

23 September 2017

Eva Sin Yan Chan

13

1 reference

23 September 2017

Carly Tuinman

14

1 reference

23 September 2017

Zhaozhao Jiang

16

1 reference

23 September 2017

George Thomas

18

1 reference

23 September 2017

Sara C Kozma

19

1 reference

23 September 2017

Katherine A Fitzgerald

21

1 reference

23 September 2017

Yonghong Wan

25

1 reference

23 September 2017

Brian D Lichty

26

1 reference

23 September 2017

language of work or name

English

0 references

publication date

4 April 2016

1 reference

23 September 2017

1 reference

23 September 2017

17

1 reference

23 September 2017

5

1 reference

23 September 2017

514-522

1 reference

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

23 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The ever-evolving role of mTOR in translation.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Maraba virus as a potent oncolytic vaccine vector

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

STING and the innate immune response to nucleic acids in the cytosol

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Host translation at the nexus of infection and immunity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Cytosolic surveillance and antiviral immunity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

STING is a direct innate immune sensor of cyclic di-GMP

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Immune signaling by RIG-I-like receptors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The STING pathway and regulation of innate immune signaling in response to DNA pathogens

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Functions and regulation of the 70kDa ribosomal S6 kinases.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Intracellular DNA recognition

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

The mammalian target of rapamycin signaling network and gene regulation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Identification of a conserved motif required for mTOR signaling

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Structural and functional analysis of pp70S6k

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Dendritic cells transfected with adenoviral vectors as vaccines

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Translational control of the innate immune response through IRF-7

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917298

Interferon regulatory factor 3 in adaptive immune responses.

2 December 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.3433

inferred from DOI database lookup

7 January 2021

based on heuristic

Use of the intracellular fluorescent dye CFSE to monitor lymphocyte migration and proliferation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.3433

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI.3433

1 reference

Dimensions Publication ID

23 September 2017

0 references

1 reference

23 September 2017

PubMed publication ID

27043414

1 reference