(Q40734787)

23 September 2017

title

The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex (English)

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23 September 2017

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Dimitry Spitkovsky

1

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23 September 2017

Steffen P Hehner

2

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23 September 2017

Thomas G Hofmann

3

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23 September 2017

Andreas Möller

4

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23 September 2017

M Lienhard Schmitz

5

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23 September 2017

language of work or name

English

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publication date

1 May 2002

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Journal of Biological Chemistry

23 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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23 September 2017

volume

277

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23 September 2017

issue

28

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23 September 2017

page(s)

25576-25582

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Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

23 September 2017

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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PKN binds and phosphorylates human papillomavirus E6 oncoprotein

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Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

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Inhibition of Bak-induced apoptosis by HPV-18 E6.

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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The Rb/E2F pathway and cancer

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Human papillomavirus E7 proteins stimulate proliferation independently of their ability to associate with retinoblastoma protein

21 January 2018

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Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

21 January 2018

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Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107.

21 January 2018

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Allosteric activation of acid alpha-glucosidase by the human papillomavirus E7 protein

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Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein

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Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis

21 January 2018

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Interaction of the fork head domain transcription factor MPP2 with the human papilloma virus 16 E7 protein: enhancement of transformation and transactivation

21 January 2018

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Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity.

21 January 2018

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Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells

21 January 2018

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Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes

21 January 2018

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Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins.

21 January 2018

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Immune evasion in human papillomavirus-associated cervical cancer

21 January 2018

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NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

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NF-kappaB and cell-cycle regulation: the cyclin connection

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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Regulation of inducible gene expression by the transcription factor NF-kappaB.

21 January 2018

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Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

21 January 2018

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Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

21 January 2018

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The dual effect of adenovirus type 5 E1A 13S protein on NF-kappaB activation is antagonized by E1B 19K.

21 January 2018

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pEF-BOS, a powerful mammalian expression vector

21 January 2018

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Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3

21 January 2018

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21 January 2018

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JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

21 January 2018

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

21 January 2018

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Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

21 January 2018

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A functional NF-kappaB binding site in the human papillomavirus type 16 long control region

21 January 2018

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Regulation of early gene expression of human papillomavirus type 16 by inflammatory cytokines

21 January 2018

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Increased tumorigenicity of human keratinocytes harboring human papillomavirus type 16 is associated with resistance to endogenous tumor necrosis factor-alpha-mediated growth limitation

21 January 2018

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Increased p50/p50 NF-kappaB activation in human papillomavirus type 6- or type 11-induced laryngeal papilloma tissue

21 January 2018

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Human papillomavirus type 16 E6-enhanced susceptibility to apoptosis induced by TNF in A2780 human ovarian cancer cell line

21 January 2018

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Functional oligomerization of purified human papillomavirus types 16 and 6b E7 proteins expressed in Escherichia coli

21 January 2018

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The IKK complex: an integrator of all signals that activate NF-kappaB?

21 January 2018

1 reference

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JNK2 and IKKbeta are required for activating the innate response to viral infection

21 January 2018

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Role of NF-κB in p53-mediated programmed cell death

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201884200

1 reference

23 September 2017

1 reference