(Q40754406)

English

A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila.

scientific article published on 5 April 2010

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scholarly article

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30 January 2020

A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila (English)

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30 January 2020

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RNA interference

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based on heuristic

inferred from title

Michael Boutros

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30 January 2020

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30 January 2020

author name string

Vanessa Gobert

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30 January 2020

Dani Osman

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30 January 2020

Stéphanie Bras

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30 January 2020

Benoit Augé

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30 January 2020

Muriel Boube

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30 January 2020

Henri-Marc Bourbon

6

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30 January 2020

Thomas Horn

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5 April 2010

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30 January 2020

Molecular and Cellular Biology

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30 January 2020

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30 January 2020

2837-2848

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30 January 2020

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30 January 2020

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update.

1 reference

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Upregulation of the Drosophila Friend of GATA gene U-shaped by JAK/STAT signaling maintains lymph gland prohemocyte potency

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Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development.

1 reference

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24 September 2017

Is Runx a linchpin for developmental signaling in metazoans?

1 reference

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24 September 2017

RUNX proteins in transcription factor networks that regulate T-cell lineage choice

1 reference

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24 September 2017

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

1 reference

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24 September 2017

STRING 8--a global view on proteins and their functional interactions in 630 organisms

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24 September 2017

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

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24 September 2017

Cross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation

1 reference

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24 September 2017

Message in a nucleus: signaling to the transcriptional machinery

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24 September 2017

The art and design of genetic screens: RNA interference.

1 reference

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24 September 2017

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

1 reference

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24 September 2017

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.

1 reference

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24 September 2017

Hematopoiesis: an evolving paradigm for stem cell biology

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24 September 2017

Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development.

1 reference

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24 September 2017

Gatekeeper function of the RUNX1 transcription factor in acute leukemia

1 reference

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24 September 2017

The GATA factor Serpent cross-regulates lozenge and u-shaped expression during Drosophila blood cell development

1 reference

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24 September 2017

Regulation of RUNX1 transcriptional function by GATA-1.

1 reference

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24 September 2017

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

1 reference

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24 September 2017

CDK8 is a stimulus-specific positive coregulator of p53 target genes

1 reference

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24 September 2017

GATA-3 - not just for Th2 cells anymore

1 reference

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24 September 2017

Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876525

24 September 2017

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

1 reference

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24 September 2017

Mediator modulates Gli3-dependent Sonic hedgehog signaling

1 reference

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24 September 2017

Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.

1 reference

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24 September 2017

Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome

1 reference

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24 September 2017

Runx1 binds positive transcription elongation factor b and represses transcriptional elongation by RNA polymerase II: possible mechanism of CD4 silencing

1 reference

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24 September 2017

Mediator as a general transcription factor

1 reference

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24 September 2017

GATA transcription factors in hematologic disease

1 reference

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24 September 2017

Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets

1 reference

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24 September 2017

GATA-1: one protein, many partners.

1 reference

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24 September 2017

Identification of JAK/STAT signalling components by genome-wide RNA interference.

1 reference

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24 September 2017

E-RNAi: a web application to design optimized RNAi constructs

1 reference

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24 September 2017

Structure of eukaryotic Mediator complexes

1 reference

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24 September 2017

Dynamic regulation of pol II transcription by the mammalian Mediator complex

1 reference

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24 September 2017

The mammalian Mediator complex and its role in transcriptional regulation

1 reference

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24 September 2017

Interactions between subunits of Drosophila Mediator and activator proteins

1 reference

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24 September 2017

The yeast Mediator complex and its regulation

1 reference

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24 September 2017

Mediator and the mechanism of transcriptional activation

1 reference

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24 September 2017

Developmental control via GATA factor interplay at chromatin domains

1 reference

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24 September 2017

Gene expression regulation and domain function of hematopoietic GATA factors

1 reference

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24 September 2017

Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis

1 reference

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24 September 2017

Core-binding factors in hematopoiesis and immune function

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24 September 2017

Genome-wide RNAi analysis of growth and viability in Drosophila cells

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24 September 2017

Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis

1 reference

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24 September 2017

Combinatorial interactions of Serpent, Lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis

1 reference

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24 September 2017

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

1 reference

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24 September 2017

Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis

1 reference

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24 September 2017

Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man

1 reference

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Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

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24 September 2017

The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila

1 reference

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24 September 2017

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

1 reference

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24 September 2017

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1 reference

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24 September 2017

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

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24 September 2017

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1 reference

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24 September 2017

The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.

1 reference

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24 September 2017

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

1 reference

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17 June 2018

Specification of Drosophila hematopoietic lineage by conserved transcription factors

1 reference

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17 June 2018

Dual role of wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila

1 reference

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19 August 2018

The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876525

19 August 2018

A GATA/RUNX cis-regulatory module couples Drosophila blood cell commitment and differentiation into crystal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876525

19 August 2018

Identification of a crystal cell-specific enhancer of the black cells prophenoloxidase gene in Drosophila.

1 reference

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19 August 2018

Mediator is a transducer of Wnt/beta-catenin signaling.

1 reference

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19 August 2018

MED220/thyroid receptor-associated protein 220 functions as a transcriptional coactivator with Pit-1 and GATA-2 on the thyrotropin-beta promoter in thyrotropes.

1 reference

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19 August 2018

Resolving embryonic blood cell fate choice in Drosophila: interplay of GCM and RUNX factors

1 reference

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19 August 2018

Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm.

1 reference

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19 August 2018

The two origins of hemocytes in Drosophila.

1 reference

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19 August 2018

Drosophila homologues of the transcriptional coactivation complex subunits TRAP240 and TRAP230 are required for identical processes in eye-antennal disc development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876525

19 August 2018

A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila

1 reference

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19 August 2018

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876525

2 December 2018

Identifiers

10.1128/MCB.01625-09

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30 January 2020

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30 January 2020

1 reference

Europe PubMed Central

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30 January 2020

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