(Q52569557)

3 May 2018

title

Mediator is a transducer of Wnt/beta-catenin signaling. (English)

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3 May 2018

author

Andreas Hecht

3

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3 May 2018

author name string

Seokjoong Kim

1

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3 May 2018

Xuan Xu

2

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3 May 2018

Thomas G Boyer

4

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3 May 2018

language of work or name

English

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publication date

24 March 2006

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3 May 2018

Journal of Biological Chemistry

published in

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3 May 2018

volume

281

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3 May 2018

page(s)

14066-14075

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3 May 2018

issue

20

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3 May 2018

Mechanisms of Wnt signaling in development

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The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

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A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

21 January 2018

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Two subunits of the Drosophila mediator complex act together to control cell affinity.

21 January 2018

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Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans.

21 January 2018

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Mediator and the mechanism of transcriptional activation

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Dynamic regulation of pol II transcription by the mammalian Mediator complex

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NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription

21 January 2018

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Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

21 January 2018

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A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation

21 January 2018

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Composite co-activator ARC mediates chromatin-directed transcriptional activation

21 January 2018

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Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

21 January 2018

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Mediator requirement for both recruitment and postrecruitment steps in transcription initiation

21 January 2018

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Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602696200

In vivo requirement of activator-specific binding targets of mediator

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602696200

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602696200

Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex

21 January 2018

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Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

21 January 2018

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Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s

21 January 2018

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Activation domain–mediator interactions promote transcription preinitiation complex assembly on promoter DNA

21 January 2018

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Association of the Mediator complex with enhancers of active genes

21 January 2018

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The RNA polymerase II machinery: structure illuminates function

21 January 2018

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The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

21 January 2018

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A component of the ARC/Mediator complex required for TGF beta/Nodal signalling

21 January 2018

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Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit

21 January 2018

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Role of metazoan mediator proteins in interferon-responsive transcription

21 January 2018

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A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II

21 January 2018

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Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon

21 January 2018

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Wnt3a plays a major role in the segmentation clock controlling somitogenesis

21 January 2018

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Cytoskeletal reorganization by soluble Wnt-3a protein signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Tetrameric oligomerization mediates transcriptional repression by the BRCA1-dependent Kruppel-associated box-zinc finger protein ZBRK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Control of pancreas and liver gene expression by HNF transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Wnt/beta-catenin and estrogen signaling converge in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

The yeast Mediator complex and its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Structure, function, and activator-induced conformations of the CRSP coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602696200

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

WNT and beta-catenin signalling: diseases and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

A transcription reinitiation intermediate that is stabilized by activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602696200

21 January 2018

Identifiers

DOI

10.1074/JBC.M602696200

1 reference

3 May 2018

PubMed ID

16565090

1 reference

3 May 2018