(Q40763756)

23 September 2017

title

Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras. (English)

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23 September 2017

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Jennifer A Brennan

1

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23 September 2017

Deanna J Volle

series ordinal

2

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23 September 2017

Oleg V Chaika

series ordinal

3

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23 September 2017

Robert E Lewis

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

10 December 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

issue

7

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23 September 2017

page(s)

5369-5377

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Activation of Ras and Other Signaling Pathways by Receptor Tyrosine Kinases

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109875200

21 January 2018

A Ras by any other name

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21 January 2018

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KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

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The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

21 January 2018

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The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

21 January 2018

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KSR modulates signal propagation within the MAPK cascade

21 January 2018

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KSR stimulates Raf-1 activity in a kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109875200

The protein kinase KSR interacts with 14-3-3 protein and Raf.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109875200

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

21 January 2018

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Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

21 January 2018

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Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

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Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling

21 January 2018

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Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors

21 January 2018

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Signal transduction: hanging on a scaffold.

21 January 2018

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Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

21 January 2018

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Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

21 January 2018

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Complex formation between RAS and RAF and other protein kinases

21 January 2018

1 reference

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

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Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

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Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus

21 January 2018

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Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

21 January 2018

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

21 January 2018

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Regulation of transcription by MAP kinase cascades

21 January 2018

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Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation

21 January 2018

1 reference

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Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK.

21 January 2018

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Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

21 January 2018

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Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism

21 January 2018

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Phosphorylation of the kinase suppressor of ras by associated kinases

21 January 2018

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A short amino acid sequence able to specify nuclear location

21 January 2018

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The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation

21 January 2018

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

21 January 2018

1 reference

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14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

21 January 2018

1 reference

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C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

21 January 2018

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One path to cell death in the nervous system

21 January 2018

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Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109875200

A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase.

21 January 2018

1 reference

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Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

21 January 2018

1 reference

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109875200

1 reference

23 September 2017

1 reference