(Q40763960)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

main subject

Clostridium difficile

0 references

author

Ignazio Castagliuolo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Laura Lovato

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

7

Giorgio Palù

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Marina Sardina

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Paola Brun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Chiara DeRos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Cristina Mastrotto

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

1 May 2004

1 reference

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27 December 2019

published in

Infection and Immunity

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

72

1 reference

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27 December 2019

issue

5

1 reference

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27 December 2019

page(s)

2827-2836

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges

27 December 2019

cites work

1 reference

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24 September 2017

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24 September 2017

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24 September 2017

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A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants

24 September 2017

1 reference

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Enhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway

24 September 2017

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24 September 2017

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Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants.

24 September 2017

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Immunomodulation using bacterial enterotoxins

24 September 2017

1 reference

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Molecular mode of action of the large clostridial cytotoxins.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

pH-induced conformational changes in Clostridium difficile toxin B

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Pathophysiology, diagnosis and treatment of Clostridium difficile infection.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Glucosylation of Rho proteins by Clostridium difficile toxin B.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Differential expression of lectin-binding sites defines mouse intestinal M-cells

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Biological activities of toxins A and B of Clostridium difficile

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Effects of Clostridium difficile toxins given intragastrically to animals

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Molecular characterization of the Clostridium difficile toxin A gene

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Cytokine response by human monocytes to Clostridium difficile toxin A and toxin B

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

The role of nasopharyngeal lymphoid tissue

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Use of Vibrio spp. for expression of Escherichia coli enterotoxin B subunit fusion proteins: purification and characterization of a chimera containing a C-terminal fragment of DNA polymerase from herpes simplex virus type 1.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

The pulmonary environment promotes Th2 cell responses after nasal-pulmonary immunization with antigen alone, but Th1 responses are induced during instances of intense immune stimulation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCR7 ligands

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Comparison of the effects of concanavalin-A and epidermal growth factor on epithelial cell proliferation in the rat intestine

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Clostridium difficile toxin A stimulates macrophage-inflammatory protein-2 production in rat intestinal epithelial cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Identification of the site of uptake of the E. coli heat-labile enterotoxin, LTB.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387895

Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization

19 August 2018

1 reference

12 December 2020

The complete receptor-binding domain of Clostridium difficile toxin A is required for endocytosis

1 reference

12 December 2020

Activation of human thymocytes by antibodies to the CD3/T-cell receptor complex: Triggering of different epitopes results in different signals

1 reference

12 December 2020

Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit

1 reference

12 December 2020

Identification of intact peanut lectin in peripheral venous blood

1 reference

12 December 2020

Clostridium difficile toxin A causes early damage to mitochondria in cultured cells

1 reference

12 December 2020

The identification of plant lectins with mucosal adjuvant activity

1 reference

12 December 2020

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

1 reference

12 December 2020

Oral immunization with the B subunit of the heat-labile enterotoxin of Escherichia coli induces early Th1 and late Th2 cytokine expression in Peyer's patches

1 reference

12 December 2020

Mucosal and systemic immunogenicity of a recombinant, non-ADP-ribosylating pertussis toxin: effects of formaldehyde treatment

1 reference

12 December 2020

10.1128/IAI.72.5.2827-2836.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102793%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

15102793

1 reference