(Q40770163)

23 September 2017

title

Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines (English)

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23 September 2017

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Chishty M

1

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23 September 2017

Reichel A

2

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23 September 2017

Siva J

3

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23 September 2017

Abbott NJ

4

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23 September 2017

Begley DJ

5

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23 September 2017

language of work or name

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1 June 2001

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Journal of Drug Targeting

23 September 2017

published in

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23 September 2017

volume

9

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23 September 2017

issue

3

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23 September 2017

page(s)

223-228

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Terfenadine (Seldane): a new drug for restoring sensitivity to multidrug resistant cancer cells

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Lack of histamine synthesis and down-regulation of H1 and H2 receptor mRNA levels by dexamethasone in cerebral endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

P-Glycoprotein, a gatekeeper in the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Cardiotoxic potential and CNS effects of first-generation antihistamines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

Carrier-mediated transport of H1-antagonist at the blood-brain barrier: a common transport system of H1-antagonists and lipophilic basic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860108997930

10.3109/10611860108997930

21 January 2018

Identifiers

DOI

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23 September 2017

1 reference