(Q40781206)

English

Phosphatidylinositol 3-kinase-dependent pathways oppose Fas-induced apoptosis and limit chloride secretion in human intestinal epithelial cells. Implications for inflammatory diarrheal states

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scholarly article

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Europe PubMed Central

PubMed publication ID

23 September 2017

Phosphatidylinositol 3-kinase-dependent pathways oppose Fas-induced apoptosis and limit chloride secretion in human intestinal epithelial cells. Implications for inflammatory diarrheal states (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

M T Abreu

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

E T Arnold

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

J Y Chow

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

K E Barrett

4

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

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publication date

10 September 2001

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

23 September 2017

276

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

47563-47574

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

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Increased small intestinal apoptosis in coeliac disease

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Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells

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Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP.

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Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate

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Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells.

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Molecular and functional characterization of the small Ca(2+)-regulated K+ channel (rSK4) of colonic crypts

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In vitro model of intestinal crypt abscess. A novel neutrophil-derived secretagogue activity

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The role of phosphoinositide 3-kinase lipid products in cell function

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21 January 2018

Signaling by distinct classes of phosphoinositide 3-kinases

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Cellular survival: a play in three Akts

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

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Pten is essential for embryonic development and tumour suppression

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Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma

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Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation

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Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

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PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

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alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway

1 reference

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21 January 2018

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

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Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

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Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

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A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

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21 January 2018

Established intestinal cell lines as model systems for electrolyte transport studies

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Synergistic action of cyclic adenosine monophosphate- and calcium-mediated chloride secretion in a colonic epithelial cell line

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Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

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Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

1 reference

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21 January 2018

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

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21 January 2018

Caspases: enemies within

1 reference

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Caspases: intracellular signaling by proteolysis

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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

1 reference

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

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Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

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Regulation of cell death protease caspase-9 by phosphorylation

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Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

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Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange

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ErbB2 and ErbB3 receptors mediate inhibition of calcium-dependent chloride secretion in colonic epithelial cells

1 reference

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A role for protein kinase cepsilon in the inhibitory effect of epidermal growth factor on calcium-stimulated chloride secretion in human colonic epithelial cells

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Neutrophil migration across model intestinal epithelia: monolayer disruption and subsequent events in epithelial repair.

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Occluding junction structure-function relationships in a cultured epithelial monolayer

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Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function

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Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins

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Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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F-actin differentially alters epithelial transport and barrier function

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Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule

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Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins

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Identifiers

10.1074/JBC.M106226200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

ResearchGate publication ID

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