(Q40794525)

23 September 2017

A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT. (English)

1 reference

23 September 2017

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protein ubiquitination

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inferred from title

cervix uterine cancer

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S Ganiatsas

1

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23 September 2017

R Dow

2

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23 September 2017

A Thompson

3

1 reference

23 September 2017

B Schulman

4

1 reference

23 September 2017

D Germain

5

1 reference

23 September 2017

language of work or name

English

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publication date

1 June 2001

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23 September 2017

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23 September 2017

20

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23 September 2017

3641-3650

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23 September 2017

28

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204501

23 September 2017

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cites work

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Regulation of cell proliferation by the E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Proteolysis and the G1-S transition: the SCF connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

A novel cyclin encoded by a bcl1-linked candidate oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

Kip1 meets SKP2: new links in cell-cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

Ubiquitination of free cyclin D1 is independent of phosphorylation on threonine 286

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

Cyclins and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

One ring to rule a superfamily of E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204501

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204501

1 reference

Dimensions Publication ID

23 September 2017

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1 reference