(Q40806178)

23 September 2017

Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4. (English)

1 reference

23 September 2017

0 references

F Peruzzi

1

1 reference

23 September 2017

M Prisco

2

1 reference

23 September 2017

A Morrione

3

1 reference

23 September 2017

B Valentinis

4

1 reference

23 September 2017

R Baserga

5

1 reference

23 September 2017

language of work or name

English

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publication date

14 May 2001

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Journal of Biological Chemistry

23 September 2017

1 reference

23 September 2017

276

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23 September 2017

25990-25996

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23 September 2017

28

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The IGF-I receptor in cancer research

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

14-3-3 proteins interact with the insulin-like growth factor receptor but not the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

14-3-3beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3'-kinase activity in 3T3L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Activation of Raf-1 by 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Isolation and characterization of mitochondria from human B lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

mGrb10 interacts with Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Isotype-specific functions of Raf kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103188200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103188200

1 reference

23 September 2017

1 reference