(Q40811026)

23 September 2017

title

Clinical validity of a DPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines (English)

1 reference

23 September 2017

13

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13 June 2020

Giuseppe Toffoli

1

1 reference

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13 June 2020

Angela Buonadonna

3

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13 June 2020

Antonino De Paoli

5

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13 June 2020

Simona Scalone

6

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13 June 2020

Gianmaria Miolo

7

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13 June 2020

Sara Lonardi

10

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13 June 2020

Giovanni Lo Re

12

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13 June 2020

Rossana Roncato

14

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13 June 2020

Eva Dreussi

15

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13 June 2020

Sara Gagno

16

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13 June 2020

Erika Cecchin

17

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13 June 2020

author name string

Luciana Giodini

2

1 reference

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13 June 2020

Massimiliano Berretta

4

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13 June 2020

Enrico Mini

8

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13 June 2020

Stefania Nobili

9

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13 June 2020

Nicoletta Pella

11

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13 June 2020

language of work or name

English

0 references

publication date

23 June 2015

1 reference

International Journal of Cancer

23 September 2017

published in

1 reference

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13 June 2020

volume

137

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13 June 2020

issue

12

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13 June 2020

page(s)

2971-2980

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Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing

13 June 2020

cites work

1 reference

Systemic therapy for colorectal cancer

21 January 2018

1 reference

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

21 January 2018

1 reference

dbSNP: the NCBI database of genetic variation

21 January 2018

1 reference

Evaluating predictive pharmacogenetic signatures of adverse events in colorectal cancer patients treated with fluoropyrimidines

21 January 2018

1 reference

DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147).

21 January 2018

1 reference

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicity

21 January 2018

1 reference

Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process

21 January 2018

1 reference

Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing

21 January 2018

1 reference

Pharmacogenetics: from bench to byte--an update of guidelines

21 January 2018

1 reference

Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity

21 January 2018

1 reference

DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis

21 January 2018

1 reference

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

21 January 2018

1 reference

Comparative functional analysis of DPYD variants of potential clinical relevance to dihydropyrimidine dehydrogenase activity

21 January 2018

1 reference

Variants in the Dihydropyrimidine Dehydrogenase, Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genes Predict Early Toxicity of 5-Fluorouracil in Colorectal Cancer Patients

21 January 2018

1 reference

Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group

21 January 2018

1 reference

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients

21 January 2018

1 reference

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

21 January 2018

1 reference

Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil

21 January 2018

1 reference

A DPYD variant (Y186C) in individuals of african ancestry is associated with reduced DPD enzyme activity

21 January 2018

1 reference

Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer

21 January 2018

1 reference

Evaluation of predictive tests for screening for dihydropyrimidine dehydrogenase deficiency.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.29654

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26099996%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference