(Q40846839)

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Analysis of function and regulation of proteins that mediate signal transduction by use of lipid-modified plasma membrane-targeting sequences

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Analysis of function and regulation of proteins that mediate signal transduction by use of lipid-modified plasma membrane-targeting sequences (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Reuther GW

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Buss JE

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Quilliam LA

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Clark GJ

4

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Der CJ

5

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

0 references

publication date

1 January 2000

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Methods in Enzymology

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Europe PubMed Central

PubMed publication ID

24 September 2017

327

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

331-350

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

The complexity of Raf-1 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The regulation of transcription by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional regulation by extracellular signals: mechanisms and specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting proteins to membranes using signal sequences for lipid modification

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression Cloning of lfc, a Novel Oncogene with Structural Similarities to Guanine Nucleotide Exchange Factors and to the Regulatory Region of Protein Kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The biology and enzymology of eukaryotic protein acylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein prenylation: more than just glue?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Detecting radiolabeled lipid-modified proteins in polyacrylamide gels

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The src protein contains multiple domains for specific attachment to membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Myristylation and palmitylation of Src family members: the fats of the matter

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Deletion of the regulatory domain of protein kinase C alpha exposes regions in the hinge and catalytic domains that mediate nuclear targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Myristylation of gag-onc fusion proteins in mammalian transforming retroviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleotide Sequence of the Rasheed Rat Sarcoma Virus Oncogene: New Mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Myristylation alters DNA-binding activity and transactivation of FBR (gag-fos) protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional significance of myristoyl moiety in N-myristoyl proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Coupled translation/prenylation of Rab proteins in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Prenylation analysis of bacterially expressed and insect cell-expressed Ras and Ras-related proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of ras acylation sites: mutagenesis and transfection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Palmitoylation of G-protein alpha subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Increasing complexity of the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural organization of the bcr gene and its role in the Ph' translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2927288-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0076-6879(00)27288-1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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