(Q40899411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

main subject

transmembrane protein

0 references

multiple drug resistance

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

D M Clarke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 February 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 November 2019

number of pages

4

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

5253-5256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10681495%20AND%20SRC:MED&resulttype=core&format=json

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

4 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

21 January 2018

1 reference

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The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Membrane topology of a cysteine-less mutant of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Superfolding of the partially unfolded core-glycosylated intermediate of human P-glycoprotein into the mature enzyme is promoted by substrate-induced transmembrane domain interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

P-glycoprotein. Associations between domains and between domains and molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Site-directed disulfide mapping of helices M4 and M6 in the Ca2+ binding domain of SERCA1a, the Ca2+ ATPase of fast twitch skeletal muscle sarcoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Drug-stimulated ATPase Activity of Human P-glycoprotein Requires Movement between Transmembrane Segments 6 and 12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.8.5253