(Q40921250)

English

Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier

scientific article published on November 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

transmembrane transport

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transmembrane protein

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1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Zhao R

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Gao F

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Goldman ID

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 November 1999

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Europe PubMed Central

PubMed publication ID

24 September 2017

Biochemical Pharmacology

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Europe PubMed Central

PubMed publication ID

24 September 2017

58

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

1615-1624

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

1 reference

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Molecular cloning of the human placental folate transporter

1 reference

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7 January 2021

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

1 reference

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7 January 2021

Folate-based thymidylate synthase inhibitors as anticancer drugs

1 reference

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Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA).

1 reference

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7 January 2021

Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol

1 reference

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7 January 2021

The characteristics of the membrane transport of amethopterin and the naturally occurring folates

1 reference

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7 January 2021

Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles: directional symmetry and anion specificity for differential mobility of loaded and unloaded carrier

1 reference

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7 January 2021

Structural requirements for anion substrates of the methotrexate transport system in L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900257-9

7 January 2021

Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 Cells

1 reference

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7 January 2021

A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

1 reference

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7 January 2021

A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.

1 reference

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7 January 2021

Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

1 reference

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7 January 2021

Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells

1 reference

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7 January 2021

Organization of the murine reduced folate carrier gene and identification of variant splice forms

1 reference

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7 January 2021

Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function

1 reference

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7 January 2021

Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells

1 reference

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7 January 2021

Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles.

1 reference

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7 January 2021

Folate-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900257-9

7 January 2021

Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

1 reference

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7 January 2021

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900257-9

7 January 2021

A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter w

1 reference

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7 January 2021

Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis

1 reference

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7 January 2021

Identifiers

10.1016/S0006-2952(99)00257-9

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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